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Organizational Structure
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Conducts basic and applied research in computational, mathematical,
and theoretical problems in molecular biology and genetics, including
genome analysis, sequence comparisons, sequence search methodologies,
macromolecular structure, dynamics and interaction, and structure/function
prediction
Establishes collaborative research projects in computational
molecular biology with biologists, chemists, mathematicians, and
computer scientists in NIH intramural laboratories, other government
agencies, academia, and industry
Consults and advises governmental agencies and research laboratories
in the application of computer-based analytical tools for studying
molecular biology
Interacts with molecular biology groups to enhance wet-bench,
laboratory-based research through the application of computational
and theoretical approaches
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Performs applied research in data representation and analysis,
including the development of computer-based systems for the storage,
management, and retrieval of knowledge relating to molecular biology,
genetics, and biochemistry
Designs database schema and specifications for representation
of various forms of molecular biology information, including nucleic
acid, protein, and structural information. These databases serve
as national resources.
Designs and develops distributed software systems from the prototype
to operational phase, which provides researchers with both local
and remote computational services
Coordinates public access to sequence, genetics, structural,
and bibliographic information by building curated and integrated
databases and, when possible, establishes linkages to external
databases
Establishes collaborative informatics research projects with
NIH intramural laboratories as well as extramural academic groups
Consults with and advises other governmental agencies and research
laboratories on advanced methods of software and database design
Develops and promotes standards for databases, data exchange,
and biological nomenclature
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Information Resources Branch (IRB)
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Plans, directs, and manages the technical operations of NCBI,
including the computer systems used for research and development
as well as the computer systems used to access public databases
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Provides technical assistance to NCBI staff and provides support
for external users of NCBI network services
Supervises network operations for the NCBI and coordinates with
other government agencies for both national and international
access to NCBI services
Organizes educational demonstrations and workshops for the biomedical
community to foster the use of NCBI's information services
Plans, develops, and manages government contracts and cooperative
agreements to procure equipment and services in support of NCBI
information functions
Serves as liaison for user support services to agencies involved
in genome projects
Performs applied research and development, provides technical
consultation and direction, and identifies user needs. Conducts
surveys to evaluate the use of NCBI-developed software in the
biology user community.
Coordinates with other governmental agencies and biology information
resources to facilitate the development of data repositories at
the NCBI
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A Board of Scientific
Counselors meets twice a year to review the research activities
of the Center.
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Revised: May 21, 2004.
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