NEWS
Lung Cancer Genome Surveys Find Many Potential Drug Targets
Five new studies have identified genetic and epigenetic alterations in hundreds of lung tumors, including many changes that could be targeted by drugs that are already available or in clinical testing.
The reports, all published this month, included genomic information on more than 400 lung tumors. In addition to confirming genetic alterations previously tied to lung cancer, the studies identified other changes that may play a role in the disease. Read more > >
Diagnostic Radiation Exposure May Raise Breast Cancer Risk in Some BRCA1/2 Mutation Carriers
Retrospective study finds any exposure before age 30 almost doubles risk of breast cancerNew Drug Improves Survival in Patients with Advanced Lung Cancer UPDATED
Experimental antibody aims to make tumor blood vessels accessible to the immune systemDrug Targeting Tumor Suppressor Shows Promise in First Human Study
Treatment designed to restore p53 activity in tumor cells is safe and shows biological activityStudy Reveals How Breast Cancer Spreads to Lymph Nodes
Off-patent drug used to treat heart failure inhibits metastasis in miceAlso in the Journals: Smoky Coal Associated with Increased Risk of Lung Cancer in Rural China
Also in the Journals: Best Practices Can Reduce Central-Line Infections in Children with Cancer
COMMENTARY
Changing Social Norms about Tobacco Use, One Campus at a Time
by Dr. Howard Koh
The assistant secretary for health describes efforts to by the Department of Health and Human Services to reduce tobacco use among young adults.
A Conversation with Dr. John Stamatoyannopoulos about ENCODE and Cancer Research
The University of Washington oncologist and ENCODE investigator discusses the Encyclopedia of DNA Elements (ENCODE) results and what they could mean for cancer research.
IN DEPTH
Building a Biobank to Explore Mysteries of the Genome
The GTEx project could help researchers study how genetic changes cause cancer and other diseasesSingled Out: Researchers Look to Single Cells for Cancer Insights
Studying individual cells may lead to better understanding of cancerFeatured Clinical Trial: Treating KSHV-Associated Multicentric Castleman Disease
Will a biological agent improve outcomes for patients with concurrent Kaposi sarcoma?
UPDATES
AHRQ Update
- Task Force Reaffirms Recommendation against Ovarian Cancer Screening
FDA Update
- FDA Approves Imaging Agent that Helps Detect Prostate Cancer
- Drug for Advanced Prostate Cancer Approved
- FDA Approves New Drug to Treat Chronic Myelogenous Leukemia
Notes
- Cancer Classroom Webinar: Culture and Literacy
- Call for Applications: NCI Clinical Assay Development Program
- New Brochure Educates Patients about Biospecimen Donation
MULTIMEDIA
Cancer Research Now: Building a Biobank
Researchers with the NCI cancer Human Biobank describe how donated tissue is collected, processed, shipped, and analyzed for the Genotype-Tissue Expression project.
Go to Video
Selected articles from past issues of the NCI Cancer Bulletin are available in Spanish.
The NCI Cancer Bulletin is produced by the National Cancer Institute (NCI), which was established in 1937. Through basic, clinical, and population-based biomedical research and training, NCI conducts and supports research that will lead to a future in which we can identify the environmental and genetic causes of cancer, prevent cancer before it starts, identify cancers that do develop at the earliest stage, eliminate cancers through innovative treatment interventions, and biologically control those cancers that we cannot eliminate so they become manageable, chronic diseases.
For more information about cancer, call 1-800-4-CANCER or visit http://www.cancer.gov.
NCI Cancer Bulletin staff can be reached at ncicancerbulletin@mail.nih.gov.