2010 National DNA Day Online Chatroom Transcript

This is just one question from an archive of the National DNA Day Moderated Chat held in April 2010. The NHGRI Director and many genomics experts from across NHGRI took questions from students, teachers and the general public on topics ranging from basic genomic research, to the genetic basis of disease, to ethical questions about genetic privacy.

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KV- How did they figure out that A went with T and C went with G?      Phyllis Frosst, Ph.D.: I currently investigate genetic discrimination, direct to consumer marketing of genetic tests and pharmacogenomics. Using paper chromatography and UV spectrophotometry, Columbia University scientists lead by Erwin Chargaff observed that there are equal molar concentration of A & T, as well as G & C in most DNA molecules. East Haven High School in CT (10th grade student)

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