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The bacterium behind one of mankind's deadliest scourges, tuberculosis, is helping researchers at the Commerce Department's National Institute of Standards and Technology (NIST) and the Department of Energy's Brookhaven National Laboratory (BNL) move closer to answering the decades-old question of what controls the switching on and off of genes that carry out all of life's functions. In a Journal of Biological Chemistry paper, the NIST/BNL team reports that it has defined—for the first time—the structure of a "metabolic switch" found inside most types of bacteria. (More)
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