Nigel P. Crawford, M.B. Ch.B., Ph.D.

Investigator, Cancer Genetics Branch
Head, Metastasis Genetics Section

Selected Publications

Yang H, Crawford N, Lukes L, Finney R, Lancaster M, Hunter KW. Metastasis predictive signature profiles pre-exist in normal tissues. Clin Exp Metastasis, 22:593-603. 2005. [PubMed]

Crawford NP, Colliver DW, Funke AA, Young MN, Kelley S, Cobbs GA, Petras RE, Galandiuk S. Characterization of genotype-phenotype relationships and stratification by the CARD15 variant genotype for inflammatory bowel disease susceptibility loci using multiple short tandem repeat genetic markers. Hum Mutat, 25:156-166. 2005. [PubMed]

Crawford NP, Ziogas A, Peel DJ, Hess J, Anton-Culver H, Hunter KW. Germline polymorphisms of SIPA1 are associated with metastasis and other indicators of poor prognosis in breast cancer. Breast Cancer Res, 8:R16. 2006. [PubMed]

Crawford NP, Qian X, Ziogas A, Papageorge AG, Boersma BJ, Walker RC, Lukes L, Rowe WH, Zhang J, Ambs S, Lowy DR, Anton-Culver H, Hunter KW. Rrp1b, a new candidate susceptibility gene for breast cancer progression and metastasis. PLoS Genet, 3:e214. 2007. [PubMed]

Crawford NP, Colliver DW, Eichenberger MR, Funke AA, Kolodko V, Cobbs GA, Petras RE, Galandiuk S. CARD15 genotype-phenotype relationships in a small inflammatory bowel disease population with severe disease affection status. Digest Dis Sci, 52:2716-2724. 2007. [PubMed]

Crawford NP, Alsarraj J, Lukes L, Walker RC, Officewala JS, Yang HH, Lee MP, Ozato K, Hunter KW. Bromodomain 4 activation predicts breast cancer survival. Proc Natl Acad Sci USA, 105:6380-6385. 2008. [PubMed]

Crawford NP, Lukes L, Walker RC, Officewala JS, Williams R, Hunter KW. The diasporin pathway: a transcriptional network that is invoked in metastasis and predicts breast cancer survival. Clin Exp Metastasis, 25:357-369. 2008. [PubMed]

Lukes L, Crawford NP, Walker R, Hunter KW. The origins of breast cancer prognostic gene expression profiles. Cancer Res, 69:310-318. 2009.[PubMed]

Hancock H, Dreher MR, Crawford N, Pollock CB, Shih J, Wood BJ, Hunter K, Frenkel V. Evaluation of Pulsed High Intensity Focused Ultrasound exposures on Metastasis in a Murine Model. Clin Exp Metastasis, 26(7):729-38. 2009. [PubMed]

Crawford NP, Yang H, Hunter KW. The metastasis efficiency modifier Ribosomal RNA Processing 1 Homolog B (RRP1B) is a chromatin-associated factor. J Biol Chem, 284:28660-28673. 2009. [PubMed]

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Last Reviewed: March 27, 2012