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Isopropylamine Safety and Health Topics:
Isopropylamine

General Description
    Synonym(s): Monoisopropylamine; 2-Aminopropane

    OSHA IMIS Code Number: 1562

    Chemical Abstracts Service (CAS) Registry Number: 75-31-0

    NIOSH, Registry of Toxic Effects (RTECS) Identification Number: RTECS NT8400000; 44678

    Department of Transportation Regulation Number (49 CFR 172.101): UN1221 Flammable Liquid

    Chemical Description and Physical Properties: Colorless liquid with a pungent, ammonia-like odor.
      molecular weight: 59
      boiling point: 90° F
      vapor pressure: 478 mm
      melting point: -139° F
    Potentially hazardous incompatibilities: Strong acids and oxidizers
Exposure Limits
    OSHA Permissible Exposure Limit (PEL) for General Industry: 5 ppm, 12 mg/m3 (TWA)

    OSHA Permissible Exposure Limit (PEL) for Construction Industry: 5 ppm, 12 mg/m3 (TWA)

    American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value (TLV): 5 ppm, 12 mg/m3 (TWA); 10 ppm, 24 mg/m3 (STEL)

    National Institute for Occupational Safety and Health (NIOSH) Recommended Exposure Limit (REL): 5 ppm (TWA); 10 ppm (STEL)
Health Factors
    Potential symptom(s): Eye, nose, throat, skin irritation; pulmonary edema; visual disturbance; skin, eye burns; dermatitis

    Health Effect(s): Irritation-Eye, Nose, Throat, Skin---Marked (HE14)

    Affected organ(s): Respiratory system, skin, eyes

    NIOSH/OSHA/DOE Health Guideline
Monitoring Methods used by OSHA
    Laboratory Sampling/Analytical Method:

    sampling media: Midget Fritted Glass Bubbler (MFGB) containing 10 mL of 0.05 M H2SO4.
    maximum volume: 100 Liters   maximum flow rate: 1.0 L/min (TWA)
    maximum volume: 15 Liters   maximum flow rate: 1.0 L/min (STEL)
    current analytical method: Gas Chromatography; GC/FID
    method reference: NIOSH Manual of Analytical Methods (NIOSH S-147)
    method classification: Fully Validated

    sampling media: Coated XAD-2 Tube (80/40 sections, 20/60 mesh); coating is 10% (w/w) 1-Naphthylisothiocyanate (NITC)
    analytical solvent: Dimethylformamide
    maximum volume: 20 Liters   maximum flow rate: 0.1 L/min (TWA)
    maximum volume: 1.5 Liters   maximum flow rate: 0.1 L/min (STEL)
    current analytical method: High Performance Liquid Chromatography; HPLV/UV
    method reference: OSHA Manual of Analytical Methods (OSHA In-house File)
    method classification: Partially Validated

    On-Site Sampling Techniques/Methods:

    device: Detector Tube
    manufacturer: AUER/MSA
    model/type: Triethylamine-5, MSA P/N 804134, AUER P/N 5086-816
    sampling information: follow manufacturer's instructions
    upper measurement limit: 30 ppm
    detection limit: approximately 1 ppm
    overall uncertainty: unknown
    method reference: on-site air secondary (manufacturer)

    device: Detector Tube
    manufacturer: Gastec
    model/type: 180
    sampling information: 1 stroke
    upper measurement limit: 110 ppm
    detection limit: 1 ppm
    overall uncertainty: 16.4% for 6 to 22 ppm, 8.2% for 22 to 110 ppm
    method reference: on-site air secondary (manufacturer)

    * All Trademarks are the property of their respective owners.
 
Revised: 07 April 2003
 
 
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  Chemical Sampling Information:
  Isopropylamine
  General Description
  Exposure Limits
  Health Factors
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