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Chemical Sampling Information: |
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| Stibine |
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General Description
Synonyms: Antimony hydride; Hydrogen antimonide; Antimony trihydride
OSHA IMIS Code Number: 2267
Chemical Abstracts Service (CAS) Registry Number: 7803-52-3
NIOSH, Registry of Toxic Effects (RTECS) Identification Number: WJ0700000
Department of Transportation Regulation Number (49 CFR 172.101) and Guide: 2676 119
NIOSH Pocket Guide to Chemical Hazards, Stibine: chemical description, physical properties, potentially hazardous incompatibilities, and more
Exposure Limits
OSHA Permissible Exposure Limit (PEL) for General Industry: 29 CFR 1910.1000 Z-1 Table -- 0.1 ppm, 0.5 mg/m3 TWA
OSHA Permissible Exposure Limit (PEL) for Construction Industry: 29 CFR 1926.55 Appendix A -- 0.1 ppm, 0.5 mg/m3 TWA
OSHA Permissible Exposure Limit (PEL) for Maritime: 29 CFR 1915.1000 Table Z-Shipyards -- 0.1 ppm, 0.5 mg/m3 TWA
American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value (TLV): 0.1 ppm, 0.51 mg/m3 TWA (TLV listed under Antimony hydride)
National Institute for Occupational Safety and Health (NIOSH) Recommended Exposure Limit (REL): 0.1 ppm, 0.5 mg/m3 TWA
Health Factors
NIOSH Immediately Dangerous To Life or Health Concentration (IDLH): 5 ppm
Potential symptoms: Headache; lassitude (weakness, exhaustion); nausea, abdominal pain; lumbar pain; hematuria; hemolytic anemia; jaundice; pulmonary irritation, cough, sore throat, wheezing, pulmonary edema (may be delayed); weak and irregular pulse.
Health Effects: Acute systemic toxicity---Hemolysis (HE4); Pulmonary edema (HE11); Highly flammable, explosion hazard (HE18)
Affected organs: Blood, liver, kidneys, respiratory system
Notes: 1) Biomonitoring for occupational exposure includes measurement of antimony in urine and blood. The half-life for the renal elimination of trivalent antimony in lead battery workers is approximately 4 days. 2) Although an EPA lab recently reported a genotoxic effect of stibine in vitro, it occurred at a minimum concentration four orders of magnitude greater than the OSHA PEL.
Date Last Revised: 08/25/2004
Literature Basis:
- NIOSH Pocket Guide to Chemical Hazards: Stibine.
- International Chemical Safety Cards (WHO/IPCS/ILO): Stibine.
- Andrewes, P., Kitchin, K.T. and Wallace, K.: Plasmid DNA damage caused by stibine and trimethylstibine. Toxicol. Appl. Pharmacol. 194(1): 41-48, 2004.
- Kentner, M., Leinemann, M., Schaller, K.H., Weltle, D. and Lehnert, G: External and internal antimony exposure in starter battery production. Int. Arch. Occup. Environ. Health 67(2): 119-123, 1995.
- Pohanish, R.P. (editor): Stibine. In, Sittig's Handbook of Toxic and Hazardous Chemicals and Carcinogens, Fourth Ed., Vol. 2. Norwich, NY: Noyes Publications, William Andrew Publishing, 2002, pp. 2090-2092.
Monitoring Methods used by OSHA
Laboratory Sampling/Analytical Method:
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sampling media: Coated Silica Gel Tube (1000/500 mg sections, 20/40 mesh); coating is HgCl2 treated
maximum volume: 50 Liters maximum flow rate: 0.2 L/min
current analytical method: Colorimetric (Rhodamine B)
method reference: NIOSH Analytical Method (NIOSH 6008)
method classification: Fully Validated
alternate analytical method: Atomic Absorption Spectroscopy; AAS/GF
method reference: OSHA Modified NIOSH Analytical Method (NIOSH 6008)
note: When analysis of a compound is requested, an elemental analysis is performed and reported as the compound. Submit as a separate sample.
On-Site Sampling Techniques/Methods:
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device: detector tube
manufacturer: Dräger
model/type: Arsine 0.05/a Tube, Code CH25001
sampling information: 20 strokes
upper measurement limit: 3 ppm
detection limit: 0.05 ppm
overall uncertainty: unknown
method reference: on-site air secondary (manufacturer)
Wipe sampling: No
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