Vaccine Safety Monitoring Activities
ISO has a three-part mission that supports CDC's leadership role:
- To perform high-quality vaccine safety research.
- To assess causality and preventable risk factors.
- To identify adverse events following immunization (AEFIs) through public health surveillance.
ISO conducts six primary vaccine safety activities:
Clinical Immunization Safety Assessment (CISA) Network
CISA studies the pathophysiology of adverse events following immunization, identifies risk factors, and develop guidance to help doctors.
Emergency Preparedness
In the event of a threat of disease outbreak in which a mass vaccination campaign is needed, emergency preparedness activities are activated to ensure that vaccines remain safe.
Emerging Infections Program (EIP) Activity
The EIP provides rapid and accurate surveillance for GBS following 2009 H1N1 flu vaccination given in 10 states.
Vaccine Adverse Event Reporting System (VAERS)
VAERS is a national reporting system. VAERS serves as an early-warning system to detect medical problems that may be related to vaccines.
Vaccine Safety Datalink Project (VSD)
VSD conducts near real-time surveillance of adverse events potentially associated with new vaccines or changes in immunization schedules.
Partnerships
ISO works with public health officials, academia, as well as international organizations such as the World Health Organization, the Brighton Collaboration, and the Department of Defense.
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