2010 National DNA Day Online Chatroom Transcript

This is just one question from an archive of the National DNA Day Moderated Chat held in April 2010. The NHGRI Director and many genomics experts from across NHGRI took questions from students, teachers and the general public on topics ranging from basic genomic research, to the genetic basis of disease, to ethical questions about genetic privacy.

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What does means E-value in BLAST? how it help to identify any unknown bacteria? is this value help for exact identification?      David Bodine, M.D., Ph.D.: I investigate the genetics of pluripotent hematopoietic stem cells (PHSCs) to improve the effectiveness of bone marrow transplantation and to find better ways to use these unique cells for gene replacement therapy. It gives the relative significance of the match of a sequence with the target sequence. it is very useful for differentiating between bacterial sequences. Sindhu Mahavidyalaya Institution, Nagpur, India (Higher Education student)

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