Kumari, D., Biacsi, R.E. and Usdin, K. Repeat expansion affects both transcription initiation and elongation in Friedreich ataxia cells. Journal of Biological Chemistry. In press. [ Full Text ]
Kumari, D. and Usdin, K. The distribution of repressive histone modifications on silenced FMR1 alleles provides clues to the mechanism of gene silencing in fragile X syndrome Human Molecular Genetics. 19: 4634-4642, 2010. [ Full Text ]
Entezam, A., Lokanga, A. R., Le, W., Hoffman, G. and Usdin, K. Potassium bromate, a potent DNA oxidizing agent exacerbates germline repeat expansion in a Fragile X premutation mouse model. Human Mutation. 31: 611-616, 2010. [ Abstract ]
Kumari, D. , Somma, V, Nakamura, A.J., Bonner, W.M., D'Ambrosio, E. and Usdin, K. The role of DNA damage response pathways in chromosome fragility in Fragile X syndrome. Nuc. Acids. Res. 37: 4385-92, 2009. [ Full Text / Abstract ]
Kumari, D. and Usdin, K. Chromatin remodeling in the noncoding repeat expansion diseases. J Biol Chem. 284: 7413-7, 2009. [ Full Text / Abstract ]
Entezam, A. and Usdin, K. ATM and ATR protect the genome against two different types of tandem repeat instability in Fragile X premutation mice. Nucleic Acids Research. 37: 6371-6377. [ Full Text ]
Usdin, K. The biological effects of simple tandem repeats: lessons from the repeat expansion diseases. Genome Res . 18: 1011-9, 2008. [ Full Text/Abstract ]
Entezam, A. and Usdin, K. ATR protects the genome against CGG.CCG-repeat expansion in Fragile X premutation mice. Nucleic Acids Res 36: 1050-6, 2008. [ Full Text / Abstract ]
Biacsi, R., Kumari, D., and Usdin, K. SIRT1 inhibition alleviates gene silencing in Fragile X mental retardation syndrome. PLoS Genetics 4:e1000017, 2008. [ Full Text / Abstract ]
Entezam, A., Biacsi, R., Orrison, B., Saha, T., Hoffman, G.E., Grabczyk, E., Nussbaum, R.L., Usdin, K. Regional FMRP deficits and large repeat expansions into the full mutation range in a new Fragile X premutation mouse model. Gene 395: 125-34, 2007. [ Full Text] / Abstract ]
Greene, E., Mahishi, L., Entezam, A., Kumari, D., Usdin, K. Repeat-induced epigenetic changes in intron 1 of the frataxin gene and its consequences in Friedreich ataxia. Nucleic Acids Res 35: 3383-90, 2007. [ Full Text] / Abstract ]
Mahishi, L. and Usdin, K. NF-Y, AP2, Nrf1 and Sp1 regulate the fragile X-related gene 2 (FXR2). Biochem J 400: 327-35, 2006. [ Full Text / Abstract ]
Greene, E., Entezam, A., Kumari, D. and Usdin, K. Ancient repeated DNA elements and the regulation of the human frataxin promoter. Genomics 85: 221-30, 2005. [ Full Text / Abstract ]
Handa, V., Goldwater, D., Stiles, D., Cam, M., Poy, G., Kumari, D. and Usdin, K. Long CGG-repeat tracts are toxic to human cells: implications for carriers of Fragile X premutation alleles. FEBS Lett 579: 2702-8, 2005. [ Full Text / Abstract ]
Handa, V., Yeh, H.J., McPhie, P. and Usdin, K. The AUUCU repeats responsible for spinocerebellar ataxia type 10 form unusual RNA hairpins. J Biol Chem 280: 29340-5, 2005. [ Full Text / Abstract ]
Handa, V., Saha, T. and Usdin, K. The fragile X syndrome repeats form RNA hairpins that do not activate the interferon-inducible protein kinase, PKR, but are cut by Dicer. Nucleic Acids Res 31: 6243-8, 2003. [ Full Text / Abstract ]