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HGP Home Spanning Disciplines,
Advancing Knowledge
Promoting Awareness,
Progress, and Applications
of the Human Genome Project

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Human Genome News Archive Edition
Vol.11, No. 3-4   July 2001
Available in PDF
 
In this issue...

In the News
* Genomes to Life
* OASCR and GTL
* DOE Microbial Cell Project
* Human Genome Draft
* Genome Perspective
* Honor for DeLisi
* New NIH Institute
* Structural Genomics
* Imaging Structures
* Synchrotron Use
* Proteome Organisation
* Breast Cancer Research
* Gene Expressions Used
* Nuclear Medicine
* Nuclear Medicine Labs
* Toxicogenomics Center
* Kettering Prize
* Zeta Phi Beta Conference
* Microbial Genomes
* Sloan-DOE Fellowships
* Ribosomes Illuminated
* In Memoriam: Walter Goad

Comparative Genomics
 * Model Organism Studies
 * Sushi Delicacy
* Arabidopsis Sequence
* AAAS Prize
* Microbial Conference
* Flyer; "Microbe Month"
* VISTA Software
Mouse
* ORNL Mouse Program
* MicroCAT Scanner Used
* Draft Sequence Achieved
* NCBI Mouse Resources
* Human-Mouse Comparisons
* MGI Allele Searching

Web, Publications, Resources
* Next-Generation Computing
* HGMIS Resources
* NSF QSB Report
* Structural Biology Basics
* Minorities and the HGP
* HGP Educational Kit
* Testing, Counseling Resources
* Biotech, ELSI Websites
* Biotech Encyclopedia
* ASM Report
* Nature Yearbook
* Next Wave Publication
* High-School Curriculum
* Education CD-ROMs
* Exploring DNA in the Classroom

Funding
* US Genome Research Funding
* UK Scholarships, PostDocs

Meeting Calendars & Acronyms
* Genome and Biotechnology Meetings
* Training Courses and Workshops
* Acronyms

* HGN archives and subscriptions

Human Genome Project Information home

ANL's Advanced Photon Source Illuminates Ribosomal Activities

Using the Advanced Photon Source at Argonne National Laboratory (ANL) to gain a detailed picture of ribosomal function, a team from the U.K. Medical Research Council Laboratory of Molecular Biology (LMB) has developed insights into how ribosomes manufacture proteins from amino acids to the exact specification of genes on DNA. Led by LMB head Venki Ramakrishnan, the team published its work in Science on May 4 [J. M. Ogle et al., Science 292(5518), 897 902].

Such information aids in understanding not only how antibiotics work but also the basis of certain kinds of resistance. If an antibiotic could induce a ribosome to make a "mistake" and add the wrong amino acid onto the protein chain, for example, such incorrectly made proteins would not function. If this happened in bacteria during development, they would be rendered ineffective. Ramakrishnan stated that pharmaceutical and biotechnological companies are keenly interested in such studies because of their potential usefulness in the design of new antibiotics that can overcome the growing problem of resistance.

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The electronic form of the newsletter may be cited in the following style:
Human Genome Program, U.S. Department of Energy, Human Genome News (v11n3-4).

Last modified: Wednesday, October 29, 2003

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