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Office Contact Info.
Phone: (631) 344-3715
Fax: (631) 344-2358
Mail address: Bldg. 490

Jean Logan

Scientist


Telephone:  (631) 344-4391
Fax:    (631) 344-7902
e-mail: jlogan@bnl.gov

See Also:
Radiotracer Chemistry and Neuroimaging

Research Interests

  • Image analysis techniques; kinetic analysis of PET data

 Education & Concurrent Positions

  • B.S. Louisiana State University
  • Ph.D. Louisiana State University
  • Instructor, Louisiana State University, 1977-1977
  • Research Associate, Brookhaven National Laboratory, 1977-1980
  • Assistant Chemist, BNL, 1980-1989
  • Associate Chemist, BNL, 1989-1994
  • Chemist, BNL, 1994-present

Selected Publications

  • Logan J., Alexoff D., and Fowler J.S.
    The use of alternative forms of graphical analysis to balance bias and precision in PET images.
    J. Cereb. Blood Flow Metab., 31(2):535-546 (2011).  PubMed
  • Wang G.-J., Geliebter A., Volkow N.D., Telang F.W., Logan J., Jayne M.C., Galanti K., Selig P.A., Han H., Zhu W., Wong C.T., and Fowler J.S.
    Enhanced Striatal Dopamine Release During Food Stimulation in Binge Eating Disorder.
    OBESITY (Silver Spring). 2011 Feb 24.  PubMed
  • Biegon A., Kim S.W., Alexoff D.L., Jayne M., Carter P., Hubbard B., King P., Logan J., Muench L., Pareto D., Schlyer D., Shea C., Telang F., Wang G.J., Xu Y., and Fowler J.S.
    Unique distribution of aromatase in the human brain: in vivo studies with PET and [N-methyl-11C]vorozole.
    Synapse, 64(11):801-807 (2010).  PubMed
  • Biegon A., Kim S.W, Logan J., Hooker J.M., Muench L., and Fowler J.S.
    Nicotine Blocks Brain Estrogen Synthase (Aromatase): In Vivo Positron Emission Tomography Studies in Female Baboons.
    Biol. Psychiatry, Feb 24 (2010) [Epub ahead of print].  PubMed
  • Logan J., Biegon A., Kim S.W., Alexoff D., and Fowler, J.S.
    Quantitating aromatase in the human brain with PET and [N-methyl-11C]vorozole([11C]VOR)
    CONFERENCE: 8th International Symposium on Functional Neuroreceptor Mapping of the Living Brain (NRM2010), University of Glasgow, Scotland, UK, July 22-24, 2010. Abstract. NEUROIMAGE, 51 (NRM2010 abstracts of Poster presentations) (2010).
  • Volkow N.D., Wang G.-J., Tomasi D., Telang F., Fowler J.S., Pradhan K., Jayne M., Logan J., Goldstein R.Z., Alia-Klein N., Wong C.T.
    Methylphenidate attenuates limbic brain inhibition after cocaine-cues exposure in cocaine abusers.
    PLOS ONE, 5(7):e1150-e1159 (2010).  PubMed
  • Wang G.J., Geliebter A., Volkow N.D., Telang F.W., Logan J., Jayne M.C., Galanti K., Selig P.A., Han H., Zhu W., Wong C.T., and Fowler J.S.
    Dopamine D4 receptors modulate brain metabolic activity in the prefrontal cortex and cerebellum at rest and in response to methylphenidate.
    Euro.Journal of Neurosci., 32(4):668-676 (2010).   PubMed
  • Wang G.-J., Telang F., Logan J., Jayne M., Ma Y., Pradhan K., Wong C.T., and Swanson J.M.
    Cognitive control of drug craving inhibits brain reward regions in cocaine abusers.
    Neuroimage, 49:2536-2543 (2010).  PubMed
  • Logan J., Fowler J.S., Dewey S.L., Volkow N.D. and Gatley J.S.
    A consideration of the dopamine D2 receptor monomer-dimer equilibrium and the anomalous binding properties of the dopamine D2 receptor ligand, N-methyl spiperone.
    J. Neural Transm., 108(3):279-286 (2001).  PubMed
  • Logan J., Fowler J.S., Volkow N.D., Ding Y.-S., Wang G.-J. and Alexoff D.L.
    A strategy for removing the bias in the graphical analysis method.
    J. Cereb. Blood Flow Metab., 21(3):307-320 (2001).  PubMed
  • Logan J., Fowler J.S., Volkow N.D., Wang G.-J., MacGregor R.R., Shea C.
    Reproducibility of repeated measures of deuterium substituted [11C]L-deprenyl ([11C]L-deprenyl D2) binding in the human brain.
    Nucl. Med. Biol., 27(1):43-49 (2000).  PubMed
  • Volkow N.D., Logan J., Fowler J.S., Wang G.-J., Gur R.C., Wong C., Felder C., Gatley S.J., Ding Y.-S., Hitzemann R. and Pappas N.
    Decreased brain dopamine activity with age is associated with impairment in frontal and cingulate metabolism.
    Am. J. Psychiatry, 157:75-80 (2000).
  • Logan J., Volkow N.D., Fowler J.S., Wang G.-J., Fischman M.W., Foltin R.W., Abumrad N.N., Vitkun S., Gatley S.J., Pappas N., Hitzemann R. and Shea C.E.
    Concentration and Occupancy of Dopamine Transporters in Cocaine Abusers with [ 11 C]-Cocaine and PET.
    Synapse, 27(4):347-356 (1997).  PubMed
  • Logan J., Fowler J.S., Volkow N.D., Wolf A.P., Dewey S.L., Schlyer D.J., Macgregor R.R., Hitzmann R., Bendriem B., Gatley S.J., Christman D.R.
    Graphical analysis of reversible radioligand binding from time-activity measurements applied to [N-11C-methyl-(-)-cocaine PET studies in human subjects.
    J. Cereb. Blood Flow Metab., 10:740-747 (1990).  PubMed

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Last Modified: March 10, 2011
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DOE, Office of Science One of ten national laboratories overseen and primarily funded by the Office of Science of the U.S. Department of Energy (DOE), Brookhaven National Laboratory conducts research in the physical, biomedical, and environmental sciences, as well as in energy technologies and national security. Brookhaven Lab also builds and operates major scientific facilities available to university, industry and government researchers. Brookhaven is operated and managed for DOE's Office of Science by Brookhaven Science Associates, a limited-liability company founded by the Research Foundation for the State University of New York on behalf of Stony Brook University, the largest academic user of Laboratory facilities, and Battelle, a nonprofit, applied science and technology organization.

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