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![Background and Overview](images/backover.gif)
The National Institutes of Health (NIH) established the
Women's Health Initiative (WHI) in 1991 to address the most common causes of
death, disability and impaired quality of life in postmenopausal women. The WHI addressed cardiovascular disease, cancer, and osteoporosis. The WHI
was a 15
year multi-million dollar endeavor, and one of the largest U.S. prevention
studies of its kind. The three major components of the WHI
were:
- a randomized controlled clinical trial of promising but
unproven approaches to prevention;
- an observational study to identify predictors of disease;
- a study of community approaches to developing healthful
behaviors.
The WHI Program Office is located within the Office of
the Director of the National Heart, Lung, and Blood
Institute (NHLBI).
Women's Health Initiative Program Office 2 Rockledge
Centre Suite 10018, MS 7936 6701 Rockledge Drive Bethesda, Maryland
20892-7936 (U.S. Postal Service) Bethesda, Maryland 20817-7936 (Express Mail
Service) Phone: (301) 402-2900 Fax: (301) 480-5158 Internet:
http://www.nhlbi.nih.gov/whi/index.html
Major Components of the Women's Health Initiative
Randomized Clinical Trial (CT)
- Hormone Therapy Trial (HT) (27,347)
- Dietary Modification Trial (DM) (48,835)
- Calcium/Vitamin D Supplementation Trial (CaD)
(36,282)
Observational Study (OS)
- CT/OS Participants:
- From 40 Clinical Centers (CC) nationwide
- 161,808 women aged 50-79;
68,132 in CT
93,676 in OS
- 17.5% overall minority recruitment:
10 CC's with
goal of 60%
Community Prevention Study (CPS)
- CPS Participants:
- at CDC funded University-based Prevention Research
Centers
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