Demonstration of Near Zero Antibiotic Prescribing for Acute Bronchitis
Tracking Information | |||||
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First Received Date ICMJE | November 10, 2010 | ||||
Last Updated Date | June 27, 2012 | ||||
Start Date ICMJE | March 2011 | ||||
Estimated Primary Completion Date | June 2013 (final data collection date for primary outcome measure) | ||||
Current Primary Outcome Measures ICMJE |
Antibiotic prescribing rate [ Time Frame: 30 days ] [ Designated as safety issue: No ] The antibiotic prescribing rate for patients with acute bronchitis |
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Original Primary Outcome Measures ICMJE | Same as current | ||||
Change History | Complete list of historical versions of study NCT01240174 on ClinicalTrials.gov Archive Site | ||||
Current Secondary Outcome Measures ICMJE |
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Original Secondary Outcome Measures ICMJE | Same as current | ||||
Current Other Outcome Measures ICMJE | |||||
Original Other Outcome Measures ICMJE | |||||
Descriptive Information | |||||
Brief Title ICMJE | Demonstration of Near Zero Antibiotic Prescribing for Acute Bronchitis | ||||
Official Title ICMJE | Demonstration of Near Zero Antibiotic Prescribing for Acute Bronchitis | ||||
Brief Summary | Studies show, guidelines state, and performance measures assert that antibiotic prescribing for uncomplicated acute bronchitis is inappropriate. However, clinicians prescribe antimicrobials in over 60% of the 22.5 million acute bronchitis visits in the United States each year. Previous successful interventions have only reduced the antimicrobial prescribing rate to 40% or 50%. It is unknown if the antimicrobial prescribing rate for acute bronchitis can be brought to near zero percent in actual practice while maintaining patient safety and satisfaction. The goal of this study is to develop an EHR-integrated algorithm for the diagnosis and treatment of adults with acute bronchitis with a goal of reducing the antibiotic prescribing rate to near zero percent. |
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Detailed Description | |||||
Study Type ICMJE | Interventional | ||||
Study Phase | |||||
Study Design ICMJE | Endpoint Classification: Efficacy Study Intervention Model: Single Group Assignment Masking: Open Label Primary Purpose: Health Services Research |
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Condition ICMJE |
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Intervention ICMJE | Behavioral: Demonstration of near zero antibiotic prescribing for patients with acute bronchitis
A controlled, continuously-monitored, implementation of an EHR-integrated diagnosis and treatment algorithm for acute bronchitis in a large, diverse primary care practice. We will use a multi-modal implementation - including computerized decision support, reporting tools, and clinician feedback - and quality improvement techniques to ensure adherence to the algorithm and reduce the antimicrobial prescribing rate to near zero percent. The duration of the intervention will be 4 years. |
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Study Arm (s) | |||||
Publications * | |||||
* Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline. |
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Recruitment Information | |||||
Recruitment Status ICMJE | Recruiting | ||||
Estimated Enrollment ICMJE | 400 | ||||
Estimated Completion Date | June 2014 | ||||
Estimated Primary Completion Date | June 2013 (final data collection date for primary outcome measure) | ||||
Eligibility Criteria ICMJE | Inclusion Criteria:
Exclusion Criteria:
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Gender | Both | ||||
Ages | 18 Years to 64 Years | ||||
Accepts Healthy Volunteers | Yes | ||||
Contacts ICMJE |
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Location Countries ICMJE | United States | ||||
Administrative Information | |||||
NCT Number ICMJE | NCT01240174 | ||||
Other Study ID Numbers ICMJE | 2010P001247 | ||||
Has Data Monitoring Committee | No | ||||
Responsible Party | Jeffrey A. Linder, Brigham and Women's Hospital | ||||
Study Sponsor ICMJE | Brigham and Women's Hospital | ||||
Collaborators ICMJE | Agency for Healthcare Research and Quality (AHRQ) | ||||
Investigators ICMJE |
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Information Provided By | Brigham and Women's Hospital | ||||
Verification Date | June 2012 | ||||
ICMJE Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP |