Targeted Screening for Taenia Solium Tapeworms
This study is not yet open for participant recruitment.
Verified February 2011 by Oregon Health and Science University
Sponsor:
Oregon Health and Science University
Collaborators:
San Marcos University School of Veterinary Medicine
Information provided by:
Oregon Health and Science University
ClinicalTrials.gov Identifier:
NCT01296958
First received: February 15, 2011
Last updated: NA
Last verified: February 2011
History: No changes posted
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Purpose
The purpose of this study is to determine whether screening and treatment of tapeworm carriers can decrease community transmission of Taenia solium parasitic infection.
| Condition | Intervention |
|---|---|
|
Tenia Solium Infection |
Drug: Niclosamide Behavioral: Community education campaign |
| Study Type: | Interventional |
| Study Design: | Allocation: Non-Randomized Endpoint Classification: Efficacy Study Intervention Model: Parallel Assignment Masking: Open Label Primary Purpose: Screening |
| Official Title: | Targeted Screening for Taenia Solium Tapeworms |
Further study details as provided by Oregon Health and Science University:
Primary Outcome Measures:
- Porcine seroprevalence [ Time Frame: Every 4 months ] [ Designated as safety issue: No ]
Secondary Outcome Measures:
- Intestinal tapeworm prevalence [ Time Frame: 16 months ] [ Designated as safety issue: No ]
| Estimated Enrollment: | 1600 |
| Study Start Date: | March 2011 |
| Estimated Study Completion Date: | August 2012 |
| Estimated Primary Completion Date: | June 2012 (Final data collection date for primary outcome measure) |
| Arms | Assigned Interventions |
|---|---|
|
Experimental: Targeted screening
Screening for intestinal tapeworm carrier followed by treatment with niclosamide as indicated.
|
Drug: Niclosamide
Single oral dose of niclosamide determined by weight (dose: 11 to 34kg receive 1 gram, 35 to 50kg receive 1.5 grams, over 50kg receive 2 grams)
|
|
Active Comparator: Education
Community education about Taenia solium prevention.
|
Behavioral: Community education campaign
Education about prevention of Taenia solium infection.
|
Eligibility| Genders Eligible for Study: | Both |
| Accepts Healthy Volunteers: | Yes |
Criteria
Inclusion Criteria:
- All community members are eligible
Exclusion Criteria:
- Inability to provide informed consent
Contacts and Locations
Please refer to this study by its ClinicalTrials.gov identifier: NCT01296958
Contacts
| Contact: Seth E ONeal, MD MPH | 5034948257 | oneals@ohsu.edu |
Locations
| Peru | |
| San Marcos University | Not yet recruiting |
| Lima, Peru | |
| Contact: Armando Gonzalez, DVM PhD 5114353189 | |
| Principal Investigator: Armando Gonzalez, DVM PhD | |
Sponsors and Collaborators
Oregon Health and Science University
San Marcos University School of Veterinary Medicine
Investigators
| Principal Investigator: | Seth E ONeal, MD MPH | Oregon Health and Science University |
| Principal Investigator: | Armando Gonzalez, DVM PhD | San Marcos University School of Veterinary Medicine |
More Information
No publications provided
| Responsible Party: | Seth O'Neal / Assistant professor, Oregon Health & Science University |
| ClinicalTrials.gov Identifier: | NCT01296958 History of Changes |
| Other Study ID Numbers: | 1R21NS069275-01 |
| Study First Received: | February 15, 2011 |
| Last Updated: | February 15, 2011 |
| Health Authority: | United States: Institutional Review Board Peru: Universidad Peruana Cayetano Heredia |
Keywords provided by Oregon Health and Science University:
|
Taenia solium cysticercosis neurocysticercosis |
Additional relevant MeSH terms:
|
Taeniasis Cestode Infections Helminthiasis Parasitic Diseases Niclosamide Anticestodal Agents Antiplatyhelmintic Agents |
Anthelmintics Antiparasitic Agents Anti-Infective Agents Therapeutic Uses Pharmacologic Actions Antinematodal Agents |
ClinicalTrials.gov processed this record on September 30, 2012
