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gimeracil
A pyridine derivative with antitumor activity. Gimeracil enhances the antitumor activity of fluoropyrimidines by competitively and reversibly inhibiting the enzyme dihydropyrimidine dehydrogenase causing decreased degradation of the fluoropyrimidines. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
| Synonym: | | chlorodihydroxypyridine | |
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| Abbreviation: | | CDHP | |
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| Chemical structure: | | 5-chloro-2,4-dihydroxypyridinediol | |
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