Technologies Available for Licensing
Current and Past Licensees of NHGRI Technologies
Patented and Patent-Pending Technologies
- Latrophilin 3, a Gene Involved in Attention Deficit Hyperactivity Disorder (ADHD)
DHHS Reference Nos.: E-312-2006 and E-187-2011
U.S. Patent 8,003,406 issued August 23, 2011
US. Provisional Patent Application 61/505,864 filed July 8, 2011
Lead Inventor: Maximillian Muenke, M.D. (NHGRI)
Marketing Description: Latrophilin 3, a Gene Involved in Attention Deficit Hyperactivity Disorder (ADHD)
Office of Technology Transfer Abstract
Federal Register Publication - Use of Adenosine Agonists to Prevent Vascular Calcification Disorders
DHHS Reference No.: E-094-2010
PCT Application PCT/US2011/030493 filed March 30, 2011
Lead Inventor: William A. Gahl, M.D., Ph.D. (NHGRI)
Marketing Description: Use of Adenosine Agonists to Prevent Vascular Calcification Disorders
Office of Technology Transfer Abstract - Device and Method for Direct Measurement of In Vivo Oxidation
DHHS Reference No.: E-099-2009
U.S. Patent Application 12/418,795 filed April 6, 2009
Lead Inventor: Charles P. Venditti, M.D., Ph.D. (NHGRI)
Marketing Description: Device and Method for Direct Measurement of In Vivo Oxidation
Office of Technology Transfer Abstract - Use of Genetic Polymorphisms to Assess Risk of Pregnancy Complications, Miscarriage, and of Bearing Children with Birth Defects
DHHS Reference No.: E-149-2005
U.S. Patent 7,879,551 issued February 1, 2011
U.S. Patent Application 13/008,528 filed January 18, 2011
Lead Inventor: Lawrence C. Brody, Ph.D. (NHGRI)
Office of Technology Transfer Abstract
Federal Register Publication - Tissue Microarrays for Rapid Molecular Profiling
DHHS Reference Nos.: E-002-1998, E-007-1999, E-272-1999, E-273-1999, and E-274-1999
U.S. Patent No. 6,699,710 issued March 2, 2004
U.S. Patent No. 6,905,823 issued June 14, 2005
Lead Inventor: Olli Kallioniemi, M.D., Ph.D.
Marketing Description: Tissue Microarrays For Rapid Molecular Profiling
Federal Register Description
- LMNA Gene and Its Involvement in Hutchinson-Gilford Progeria Syndrome (HGPS) and Arteriosclerosis
DHHS Reference No.: E-020-2003
U.S. Patent 7,297,492 issued November 29, 2007
U.S. Patent Application 11/870,234 allowed June 12, 2011
Lead Inventors: B. Maria H. Eriksson, Ph.D. and Francis S. Collins, M.D., Ph.D. (NHGRI)
Marketing Description: LMNA Gene and Its Involvement in Hutchinson-Gilford Progeria Syndrome (HGPS) and Arteriosclerosis
Office of Technology Transfer Abstract
Federal Register Publication
News Release - Farnesyltransferase Inhibitors for Treatment of Laminopathies, Cellular Aging and Atherosclerosis
DHHS Reference No.: E-055-2005
U.S. Patent 7,838,531 issued November 23, 2010
U.S. Patent Application 12/905,838 filed October 15, 2010
Lead Inventors: Leslie B. Gordon, M.D., Ph.D. (Progeria Research Foundation) and Francis S. Collins, M.D., Ph.D. (NHGRI)
Marketing Description: Farnesyltransferase Inhibitors for Treatment of Laminopathies, Cellular Aging and Atherosclerosis
Office of Technology Transfer Abstract
Federal Register Description
- Gene Mutation for Parkinson's Disease
DHHS Reference No.: E-190-1997
U.S. Patent 7,001,720 issued February 21, 2006
Lead Inventor: Mihael H. Polymeropoulos, M.D. (NHGRI)
Office of Technology Transfer Abstract
News Release - Gene for Multiple Endocrine Neoplasia Type 1 (MEN1)
DHHS Reference No.: E-094-1997
U.S. Patent 7,358,347 issued April 15, 2008
Lead Inventors: Settara Chandrasekharappa, Ph.D. (NHGRI) and Francis S. Collins, M.D., Ph.D. (NHGRI)
Office of Technology Transfer Abstract
News Release - Methods for Detecting Cervical Cancer
DHHS Reference No.: E-012-1997
U.S. Patent 5,919,624 issued July 6, 1999
Lead Inventor: Thomas K. Ried, M.D. - AIB1, A Novel Steroid Receptor Co-Activator Amplified in Human Breast Cancer
DHHS Reference No.: E-018-1997
U.S. Patent 6,562,589 issued May 13, 2003
U.S. Patent 7,232,890 issued June 19, 2007
Lead Inventor: Paul Meltzer, M.D., Ph.D. (NHGRI)
Office of Technology Transfer Abstract
News Release
Research Materials
Mouse Models
- Mouse Model of Hutchinson-Gilford Progeria Syndrome and Vascular Abnormalities
DHHS Reference No.: E-243-2011; Research Material
Lead Inventors: Michael R. Erdos (NHGRI) and Francis S. Collins, M.D., Ph.D. (NHGRI)
Marketing Description: Mouse Model of Hutchinson-Gilford Progeria Syndrome and Vascular Abnormalities
- Murine Model of Niemann-Pick C Disease
DHHS Reference No: E-004-2011/0; Research Materials
Lead Inventor: William J. Pavan Ph.D. (NHGRI)
Marketing Description: Pamela L. Schwartzberg, M.D., Ph.D. (NHGRI)
Marketing Description: Murine C57BL/6J Embryonic Stem Cell Lines Generated Using Serum-Free Media
Office of Technology Transfer Abstract - SAP/SH2D1A Knockout Mice: A Model for X-linked Lymphoproliferative Disease
DHHS Reference No.: E-343-2003; Research Materials
Lead Inventor: Pamela L. Schwartzberg, M.D., Ph.D. (NHGRI)
Marketing Description: SAP/SH2D1A Knockout Mice: A Model for X-linked Lymphoproliferative Disease
Office of Technology Transfer Abstract
Federal Register Description - Tec Kinase Deficient Mice
DHHS Reference Nos.: E-178-2003/0 and E-178-2003/1; Research Materials
Lead Inventor: Pamela L. Schwartzberg, M.D., Ph.D. (NHGRI)
Marketing Description: Tec Kinase Deficient Mice
Office of Technology Transfer Abstract
Federal Register Description
Other Research Materials
- Human Melanoma Cell Lines with ERBB4 Mutations
DHHS Reference No.: E-229-2010; Research Materials
Lead Inventor: Yardena Samuels, Ph.D. (NHGRI)
Marketing Description: Human Melanoma Cell Lines with ERBB4 Mutations
Office of Technology Transfer Abstract
- Human Melanoma Metastasis Cell Line with Isocitrate Dehydrogenase (IDH1) R132 Mutation
DHHS Reference No.: E-232-2010; Research Materials
Lead Inventor: Yardena Samuels, Ph.D.(NHGRI)
Marketing Description: Human Melanoma Metastasis Cell Line with Isocitrate Dehydrogenase (IDH1) R132 Mutation
Office of Technology Transfer Abstract - Novel Genotoxic Detection Assays
DHHS Reference Nos.: E-215-2010 and E-108-2008; Research Materials
Lead Inventor: Kyungjae Myung, Ph.D. (NHGRI)
Marketing Description: Novel Genotoxic Detection Assays - Neural Crest-Melanocyte cDNA Based Microarray Analysis for Human Skin Pigmentation Research
DHHS Reference No.: E-014-2002; Research Materials
Inventors: William Pavan, Ph.D. (NHGRI) and Stacie K. Loftus, Ph.D. (NHGRI)
Office of Technology Transfer Abstract
Federal Register Publication
- Monoclonal Antibody to the Protein NCOA6 (Also Called ASC-2 and AIB-3)
DHHS Reference No.: E-168-2005; Research Materials
Lead Inventor: Paul S. Meltzer, M.D., Ph.D. (NHGRI)
Office of Technology Transfer Abstract
Federal Register Description
For information on collaborative research opportunities and/or NHGRI technologies available for licensing, contact:
Claire T. Driscoll
Director, Technology Transfer Office
E-mail: cdriscol@mail.nih.gov
Anna Solowiej, Ph.D., J.D.
Technology Transfer Specialist
E-mail: solowieja@mail.nih.gov
Address for First Class Mail
Technology Transfer Office
National Human Genome Research Institute (NHGRI)
National Institutes of Health (NIH)
5635 Fishers Lane, Suite 3058, MSC 9307
Bethesda, MD 20892-9307
Phone: (301) 402-2537
Fax: (301) 402-9722
Address for Courier Deliveries (FedEx, UPS, etc.)
Technology Transfer Office
National Human Genome Research Institute (NHGRI)
National Institutes of Health (NIH)
5635 Fishers Lane, Suite 3058
Rockville, MD 20852
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Last Updated: June 22, 2012