Monday, February 13, 2012 |
3:00 – 3:30 p.m. |
Registration and Light Refreshments |
3:30 – 3:35 p.m. |
Introduction and Goals Robert Star, National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) Jeffrey Kopp, NIDDK |
3:35 – 4:20 p.m. |
Overview: Principles of Stereology and Applications to Research Settings John Bertram, Monash University, Australia |
4:20 – 4:40 p.m. |
Discussion |
4:40 – 5:10 p.m. |
Glomerular Numbers: Population Differences and Clinical Outcomes Wendy Hoy, The University of Queensland, Australia |
5:10 – 5:30 p.m. |
Discussion |
5:30 – 6:30 p.m. |
Panel Discussion: Challenges and Unresolved Issues in Determining Glomerular Number in Autopsy and Biopsy Studies John Bertram (Chair), Monash University, Australia Bryan Myers, Stanford University Julie Ingelfinger, Harvard University Michael Mauer, University of Minnesota Kathryn White, Newcastle University, United Kingdom |
6:30 p.m. |
Adjourn for the Day |
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Tuesday, February 14, 2012 |
7:30 – 8:00 a.m. |
Continental Breakfast |
8:00 – 8:45 a.m. |
Podocyte Number: Methods to Estimate Podocyte Number Kevin Lemley, University of Southern California |
8:45 – 9:00 a.m. |
Discussion |
9:00 – 9:30 a.m. |
Genetic Variation in Podocyte Number: Lessons From Mice Erwin Bottinger, Mount Sinai Hospital School of Medicine |
9:30 – 9:45 a.m. |
Discussion |
9:45 – 10:15 a.m. |
Correlations Between Podocyte Number, Podocyte Volume, and Podocyte Loss Roger Wiggins, University of Michigan |
10:15 – 10:30 a.m. |
Discussion |
10:30 – 10:45 a.m. |
Break |
10:45 – 11:30 a.m. |
Panel Discussion: Is it Possible to Accurately Measure Podocyte Number in Clinical Biopsy Material? Kevin Lemley (Chair), University of Southern California Behzad Najafian, University of Washington John Basgen, Charles R. Drew University of Medicine and Science Jennifer Weil, NIDDK Susanne Nicholas, University of California, Los Angeles |
11:30 a.m. – 12:15 p.m. |
Quantitative Morphology to Generate Surrogate Outcomes: Morphologic Changes as Surrogate Outcomes – How Are These Defined and Validated? FDA Perspective. Aliza Thompson and Lynne Yao, U.S. Food and Drug Administration (FDA) |
12:15 – 12:45 p.m. |
Discussion |
12:45 – 1:45 p.m. |
Lunch |
1:45 – 2:15 p.m. |
Frontiers: Imaging Approaches to Cortical Volume and Glomerular Number Kevin Bennett, Arizona State University |
2:15 – 2:45 p.m. |
Panel Discussion Norbert Gretz, Universität Heidelberg, Germany Takamune Takahashi, Vanderbilt University |
2:45 – 3:45 p.m. |
Breakout Sessions
- Glomerular Area and Volume
John Bertram, Monash University, Australia Wendy Hoy, The University of Queensland, Australia
- Interstitial Capillaries
Michael Mauer, University of Minnesota Agnes Fogo, Vanderbilt University
- Interstitial Fibrosis
Kevin Lemley, University of Southern California Cindy Nast, Cedars – Sinai
- Digital Pathology
Stephen Hewitt, National Cancer Institute Laura Barisoni, New York University Langone Medical Center |
3:45 – 4:15 p.m. |
Break |
4:15 – 4:45 p.m. |
Breakout Reports and Summary Kevin Lemley, University of Southern California |
4:45 p.m. |
Adjournment |