Announcements

EPA Health Advisory for Perchlorate - Jan 2009 (PDF)

EPA report on new Health Advisory Goal for perchlorate issued Jan 8, 2009
 

FDA perchlorate total diet Study Questions and Answers (DOC)

FDA total diet study - Talking points (DOC)

General Information

Findings from Perchlorate Sampling  - Article from EM Journal (PDF)

Article co-authored by California Regulators and DoD personnel summarizes the process and  findings of DoD-CA perchlorate prioritization effort and national efforts to find out if DoD a major contributor to perchlorate found in drinking water supplies.
 

Reports

AFIERA slides (PDF)

Ecological Effects of Perchlorate
 

A Hybrid System to Remove Perchlorate From Drinking Waters (PDF)

Information related to various treatment technologies for perchlorate.
 

Ammonium Perchlorate Workers (PDF)

Perchlorate Human Health Effects Materials
 

Amphibian Metamorphosis (PPT)

Ecological Effects of Perchlorate
 

ATSDR Draft profile (PDF)

Perchlorate Human Health Effects Materials
 

ATSDR Staff Report on Genetic Factors and Perchlorate (PDF)

Genetic Factors that Might Lead to Different Responses in Individuals Exposed to Perchlorate Franco Scinicariello, H. Edward Murray, Lester Smith, Sharon Wilbur, and Bruce A. Fowler doi:10.1289/ehp.8076 (available at http://dx.doi.org/)
 

August 2007 (PDF)

DoD Perchlorate Handbook Aug 2007
 

AWWA Report 2005 (PDF)

AWWA report on sources of perchlorate in the environment.
 

Biological Treatment of Groundwater Containing Perchlorate Using Fluidized Bed Reactors (PDF)

Information related to various treatment technologies for perchlorate.
 

Bioremediation of Perchlorate in Groundwater and Reverse Osmosis Rejectates (PDF)

Information related to various treatment technologies for perchlorate.
 

Biotreatment of Perchlorate in Groundwater (PDF)

Information related to various treatment technologies for perchlorate.
 

Braverman (PDF)

Perchlorate Human Health Effects Materials
 

CDC Q and A (DOC)

This document is for use by CDC officials responding to press inquiries - however it is also useful for any DoD official that is speaking to stakeholders about perchlorate.
 

Commercial Systems Treating both High  and  Low Strength Perchlorate Applications Utilizing Ion Exchange (PDF)

Information related to various treatment technologies for perchlorate.
 

Cost-Effective Bioremediation of Perchlorate in Soil and Groundwater (PDF)

Information related to various treatment technologies for perchlorate.
 

Cover Letter to 2005 Report to Congress (PDF)

DoD 2005 Report to Congress on perchlorate in the southwest. DoD cover letter
 

Efficient Removal of Perchlorate From Contaminated Water by Highly Selective Regenerable Bifunctional Resins (PDF)

Information related to various treatment technologies for perchlorate.
 

Efficient Removal of Perchlorate From Contaminated Water by Highly Selective Regenerable Bifunctional Resins Abstract (PDF)

Information related to various treatment technologies for perchlorate.
 

Enhanced Natural Attenuation of Perchlorate in Soils Using Electrokinetic Injection (PDF)

Information related to various treatment technologies for perchlorate.
 

EPA Draft ERD (PDF)

Perchlorate Human Health Effects Materials
 

EPA Fert. Study May 2001 (PDF)

EPA study on the potential natural and man-made  sources of perchlorate in the environment.
 

EPA presentation (PDF)

Perchlorate Handbook memo to DASs 1 May 06.pdf
 

EPA Study 2 (PDF)

EPA study on the potential natural and man-made  sources of perchlorate in the environment.
 

Perchlorate Removal Using Tailored Granular Activated Carbon and Chemical Regeneration (PDF)

Information related to various treatment technologies for perchlorate.
 

Perchlorate Southwest (PDF)

DoD 2005 Report to Congress on perchlorate in the southwest
 

Perchlorate Thyroid NHANES 01-02.pdf (PDF)

Urinary Perchlorate and Thyroid Hormone Levels in Adolescent and Adult Men and Women Living in the United States
 

Perchlorate Treatment Technologies (PDF)

Information related to various treatment technologies for perchlorate.
 

Perchlorate_White Paper_Final_32.doc (DOC)

The  white paper summarizes the presentations, discussions and future initiatives from the April 2006 Seminar on Perchlorate in Groundwater: Time to Put New Technology to Work that was hosted by the Water Resources Institute and the Office of Technology Transfer and Commercialization at California State University, San Bernardino, CA.  As a result of issues expressed at the Seminar, the next endeavor will be assembling an expert panel to prepare a Guide for Implementing New Technologies in Groundwater Treatment for water providers, researchers and responsible parties to guide newcomers through the regulatory process which involves multiple agencies.
 

Pilot Treatability Study Aerojet Sacramento, CA (PDF)

Information related to various treatment technologies for perchlorate.
 

Propellant Residues on Ranges (PDF)

Study on the potential natural and man-made  sources of perchlorate in the environment.
 

Regulation of Perchlorate under the SDWA - 2001 (PPT)

Information regarding the regulation of perchlorate by federal and state agencies.
 

Relative Source Contributions to the Food Chain for perchlorate (PDF)

Relative Source Contributions to the Food Chain for perchlorate
 

Removal of Perchlorate from Groundwater at the Longhorn Army Ammunition Plant (PDF)

Information related to various treatment technologies for perchlorate.
 

Review: Individuals respond to perchlorate differently (PDF)

Perchlorate has been detected in groundwater in many parts of the United States, and recent detection in vegetable and dairy food products indicates that contamination by perchlorate is more widespread than previously thought. Perchlorate is a competitive
 

SERDP Perchlorate Research (PDF)

Information related to various treatment technologies for perchlorate.
 

SERDP Report (PDF)

SERDP study on the potential natural and man-made  sources of perchlorate in the environment.
 

smoking and perchlorate (PDF)

Perchlorate Human Health Effects Materials
 

Survey of Fertilizers and Related Materials for Perchlorate (PDF)

Information related to various treatment technologies for perchlorate.
 

Technical Status Report Perchlorate Treatment Technologies First Edition (PDF)

Information related to various treatment technologies for perchlorate.
 

TERA Peer Review (PPT)

Perchlorate Human Health Effects Materials
 

The influence of Humeric Substances and Sulfate on the Removal of Perchlorate from a GW by Ion-Exchange Resins (PDF)

Information related to various treatment technologies for perchlorate.
 

Thyroid Function in Newborns (DOC)

Perchlorate Human Health Effects Materials
 

Time-Release Electron Donor Technology for the Accelerated Bioremediation of Perchlorate (PDF)

Information related to various treatment technologies for perchlorate.
 

Titanous Ions Destroy Perchlorates (PDF)

Information related to various treatment technologies for perchlorate.
 

Treatment of Perchlorate and Other Contaminants to Produce Drinking Water (PDF)

Information related to various treatment technologies for perchlorate.
 

University of South Florida Review (DOC)

Perchlorate Human Health Effects Materials
 

US DoD Perchlorate Treatment Technology Workshop San Antonio, Texas (PDF)

Information related to various treatment technologies for perchlorate.
 

USGS Report (PDF)

USGS study on the potential natural and man-made  sources of perchlorate in the environment.
 

Federal Remediation Technologies Roundtable General Meeting (PDF)

Information related to various treatment technologies for perchlorate.
 

Fertilizer from Chile puts perchlorate on the table (PDF)

Study on the potential natural and man-made  sources of perchlorate in the environment.
 

GAO Sampling Tracking for Perchlorate May 2005 (PDF)

GAO Reports and Letters on sampling tracking for perchlorate, May 2005.
 

Gaps by TERA (PPT)

Perchlorate Human Health Effects Materials
 

GREEN PYROTECHNIC FLARE COMPOSITIONS (PDF)

Information on perchlorate replacements including research and development on replacements.
 

In Situ Bioremediation (PPT)

SERDP Funded R and D on Perchlorate
 

In Situ Bioremediation of Perchlorate in Groundwater (PDF)

Information related to various treatment technologies for perchlorate.
 

In-Situ Bioremediation of Perchlorate in Groundwater (PDF)

Information related to various treatment technologies for perchlorate.
 

In Situ Perchlorate Bioremediation for Soil and Groundwater (PDF)

Information related to various treatment technologies for perchlorate.
 

In Situ Removal of Perchlorate From Groundwater (PDF)

Information related to various treatment technologies for perchlorate.
 

IPSC Eco Subcommittee (PDF)

Ecological Effects of Perchlorate
 

Israel Health Study (PDF)

Regulating Perchlorate CIO43 in Drinking Water: Protecting Public Health Gary Winston and Yona Amitai Departments of Environmental Health and Mother, Child, and Adolescent Health, Israel Ministry of Health, Jerusalem.
 

M115A2 Ground Burst Simulator and M116A1 Hand Grenade (PDF)

Information on perchlorate replacements including research and development on replacements.
 

March 2006 Draft Final (PDF)

DoD Perchlorate Handbook March 2006
 

May 2007 Update (PDF)

DoD Perchlorate Handbook May 2007
 

Mechanisms of Perchlorate Degradation: An Overview (PDF)

Information related to various treatment technologies for perchlorate.
 

Mechanistic Data (PDF)

Perchlorate Human Health Effects Materials
 

Navy Involvement with Perchlorate Issues and an Overview of Activities at Naval Weapons Industrial Reserve Plant McGregor, TX (PDF)

Information related to various treatment technologies for perchlorate.
 

Neonatal T4 Thyroxine (PDF)

Perchlorate Human Health Effects Materials
 

Newborn to Cancer (PPT)

Perchlorate Human Health Effects Materials
 

Nonpoint Sources of Perchlorate (PDF)

Study on the Nonpoint Sources of Perchlorate in the environment.
 

Oregon Draft HC (PDF)

A draft health consultation of an exposure investigation regarding perchlorate. It stems from a Health Consultation that was conducted in Oregon and released in December 2006.
 

Oregon Perchlorate EI summary (DOC)

A summary of an exposure investigation regarding perchlorate. It stems from a Health Consultation that was conducted in Oregon and released in December 2006.
 

Pathology (PDF)

Perchlorate Human Health Effects Materials
 

Perchlorate Behavior in a Municipal Lake Following Fireworks Displays (PDF)

Perchlorate salts of potassium and ammonium are the primary oxidants in pyrotechnic mixtures, yet insufficient information is available regarding the relationship between fireworks displays and the environmental occurrence of perchlorate.
 

Perchlorate Degradation in Bench- and Pilot-Scale Ex-Situ Reactors (PDF)

Information related to various treatment technologies for perchlorate.
 

Perchlorate Exposure are Safe for Pregnant Women (PDF)

Perchlorate ATA News 6 Oct 2007 press release on pregnant women
 

Perchlorate Exposure of the US Population 2001 2002.pdf (PDF)

Perchlorate Exposure of the US Population
 

Perchlorate in Groundwater (PDF)

Information related to various treatment technologies for perchlorate.
 

Perchlorate Isotope Analysis (PDF)

Study on the potential natural and man-made  sources of perchlorate in the environment.
 

Policy

EPA 2008 Revised Assessment Guidance on Perchlorate (PDF)

EPA JAn 2009 guidance update on Assessment of Perchlorate.
 

News

American Thyroid Assoc New Release (PDF)

Contrary to Previous Studies, Low Levels of Perchlorate Exposure Are Safe For Pregnant Women.  New Release from ATA, October 2007
 

Presentations

Background Concentrations of Perchlorate and its Impact on Site Assessment (PDF)

A presentation entitled, Background Concentrations of Perchlorate and its Impact on Site Assessment, by Andrew Jackson, Srinath Rajagopalan, Balaji Rao, Todd Anderson, Ken Rainwater,(Water Resources Center, Texas Tech University) David Stonestrom, Lynne Fahlquist, Greta Orris (United States Geological Survey) and Greg Harvey (USAF)
 

Biomonitoring Data on Thyroid-Active Compounds: Database and Issues Regarding (PDF)

Presentation slides from Biomonitoring Data on Thyroid-Active Compounds: Database and Issues Regarding Variability and Interpretation, by Ben Blount, Division of Laboratory Sciences, National Center for Environmental Health,
Centers for Disease Control and Prevention.
May 2008
 

Meetings

Perchlorate Risk Assessment Symposium (PDF)

Agenda for Perchlorate Symposium held in conjunction with the Society of Toxicologists meeting in Seattle, Wa, the week of March 17
 

Stable Isotopic Composition of Chlorine and Oxygen in Synthetic and Natural Perchlorate (PDF)

Natural Perchlorate Has a Unique Oxygen Isotope Signature (PDF)

The Origin of Naturally Occurring Perchlorate: The Role of Atmospheric Processes (PDF)

Perchlorate Isotope Forensics (PDF)

Society of Toxicology Perchlorate Symposium Agenda - 2008 (PDF)

References

Alternative Causes of Widespread, Low Concentration Perchlorate Impacts to Gro (PDF)

A report on Alternative Causes of Widespread, Low Concentration Perchlorate Impacts to Groundwater, Strategic Environmental Research and Development Program (SERDP), 5 May 2005
 

ATSDR Toxicological Profile for Perchlorates, September 2008 (PDF)

The Agency for Toxic Substances and Disease Registry (ATSDR) has released a final perchlorate toxicological profile.  The 299 page profile discusses health effects public health risk of perchorate exposure.  The profile includes a Minimal Risk Level for oral exposures with a chronic reference dose (RfD) of 0.0007 mg/kg/day for the chronic oral MRL for the perchlorate anion. This value is based on a 2005 National Academy of Sciences report and is the value that EPA has also adopted.  The results from newer studies did not change ATSDRs bottom-line recommendation.
 

Blount NHANES perchlorate study - SOT symposium presentation (PDF)

Dr. Blount has graciously provided the presentation on good faith that it will not be misquoted or quoted out of context.  We request that anyone who receives these presentations and wishes to cite, quote or otherwise use them contact the presenter. Although as a govt employee I would think this ppt was public.
 

Breast Milk Iodine and Perchlorate Concentrations (PDF)

Perchlorate exposure was not significantly correlated with breast milk iodine concentrations.  Perchlorate was detectable in infant formula, but at lower levels than in breast milk.  47% of women sampled may have been providing breast milk with insufficient iodine to meet infants requirements.
 

Effect of Iodine Status and Gender on Perchlorate Inhibition of Iodine Uptake (PDF)

Powerpoint from SOT  meeting on perchlorate risk assessment.  Not for wide distribution - material will be placed in press.
 

EHP Doug Crawford-Brown (PDF)

Intersubject Variability of Risk from Perchlorate in Community Water Supplies
 

EPA study of perchlorate impacts on brain development (PDF)

This study concludes that there is irreparable damage to brain function from developmental exposure to perchlorate. However the studies are down 4x greater than environmental exposures
 

EST vitamins perchlorate (PDF)

EST article on vitamins and perchlorate
 

Summary of Parker, et al. (2008) Perchlorate in groundwater: (DOC)

Parker, et al. (2008) Perchlorate in groundwater: A synoptic survey of pristine sites in the coterminus United States. Environ. Sci. Technol. 42(5): 1465-1471. Authors used a network of volunteers to collect 326 groundwater samples, avoiding areas of EAP-documented use or release. Of the 326 samples, 147 (45%) were below the method detection limit (40 ng/L), 42 (13%) were between the MDL and the method reporting limit (120 ng/L). Of the 137 samples that could be quantified, most (109) contained less than 1000 ng/L of perchlorate; the remaining 28 contained from 1000-10,400 ng/L. Perchlorate concentrations were positively-correlated with nitrate levels, but not with chloride concentrations.
 

Summary of Tran, et al. 2008 article on active transport of perchlorate into t (DOC)

Tran, N., et al. (2008) Thyroid stimulating hormone increases active transport of perchlorate into thyroid cells. Am J. Physiol Endocrinol. Metab., 26 Feb 2008 (e-pub ahead of publication). Using an in vitro system, authors found that perchlorate is actively transported into thyroid cells, and this transport increases in a dose-related manner when treated with TSH. Addition of iodine appeared to competitively-inhibit perchlorate transport. The highest concentration of perchlorate, 100 micromole/L, did not inhibit cell proliferation over a 72 hour period.
 

Ting et al 2006 EHP Perchlorate (PDF)

An article from the Journal Env. Health Perspectives from Ting et al that describes the basis for the Calif. public health goal of 6 ppb in water.
 

Evaluation of the EPA Preliminary Remediation Goal (PRG) for Perchlorate (PDF)

Technical paper, Evaluation of the U.S. EPA/OSWER Preliminary Remediation Goal (PRG) for Perchlorate in Groundwater: Focus on Exposure to Nursing Infants the authors (Gary L. Ginsberg, Dale B. Hattis, R. Thomas Zoeller and Deborah C. Rice).
 

Howd on Perchlorate at SOT perchlorate symposium (PDF)

Dr. Howd has graciously provided the presentation on good faith that it will not be misquoted or quoted out of context.  We request that anyone who receives these presentations and wishes to cite, quote or otherwise use them contact the presenter at the provided email addresses beforehand.
 

Lamm ppt on Perchlorate at SOT perchlorate sypmosium (PDF)

Dr. Lamm has graciously provided the presentation on good faith that it will not be misquoted or quoted out of context.  We request that anyone who receives these presentations and wishes to cite, quote or otherwise use them contact the presenter at the provided email addresses beforehand.
 

Links to  some presentations on perchlorate risk assessment science in 2008

To view the presentations by Drs. Amitai, Braverman, Gibbs, Goodman, Howd, and Lamm, please go to http://www.hhrr.com/perchloratesymposium.html, click on the Symposium Presentations tab in the page header, and type the following Username and password in the spaces provided. Username: visitor  Password: talks2008
 

Link to some papers presented at 2008 SOT perchlorate symposium

Presentations on latest perchlorate risk research presented at a Society of Toxicology side bar meeting called the Perchlorate Symposium.