Nature Biotechnology - CURRENT ISSUE : January 2012 - Vol 30 No 1
LATEST HIGHLIGHTS
Current Issue
Mapping interactions between chromosomes
Article by Kalhor et al.Genome function is influenced by the three-dimensional organization of chromosomes. Kalhor et al. experimentally detect low-frequency intra- and interchromosomal interactions previously obscured by noise and use these data to model the genome architectures of populations of cells.
Current Issue
Comparing whole-genome sequencing
Analysis by Lam et al.Over 90% of human whole-genome sequencing has been performed using instruments from two companies, Illumina and Complete Genomics. Lam et al. sequence the same DNA samples with both instruments and compare their performance for calling insertions, deletions and single-nucleotide variants.
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Building a biotech today means staying on top of what investors want and how exits are found.
Current Issue
Reinventing clinical trials
Feature by AllisonAs R&D costs spiral for drug developers, disruptive approaches to clinical trial design and management are gaining traction. Get ready for electronic data capture, precompetitive data sharing, virtual trials and a variety of bold new paradigms.
Current Issue
Rice genomic markers
Resource by Xu et al.A catalog of genetic variation in a crop species facilitates marker-assisted breeding, gene mapping and analysis of elite traits. Xu et al. resequenced 40 cultivated and 10 wild rice accessions to >15 x coverage, yielding 6.5 million single-nucleotide polymorphisms and 808,000 small insertions and deletions.
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Nature Biotechnology's blog about international life science entrepreneurship.
Current Issue
Embryonic stem cell pioneer Geron exits field
News by FrantzGeron announced in November that it was halting its phase 1 trial of its human embryonic stem cell-derived oligodendrocyte cell product, a decision that had many wondering where this leaves the field.
NEW! Impact Factor
The 2010 impact factor of Nature Biotechnology is 31.1, first among journals in the field of biotechnology, according to the Thomson Reuters Journal Citation Reports.
Sponsored Collection
Transcription activator-like (TAL) effector nucleases are a powerful new tool in genome engineering. This collection of articles is brought to you with support from Cellectis bioresearch.
Special Section
Data filters separate true genetic variants in sequencing data from sequencing errors, but their effectiveness is difficult to assess. Reumers et al. use the genome sequences of monozygotic twins to evaluate the performance of filters individually and in combination, leading to a 290-fold reduction in error rate in calling single-nucleotide variants.
