Welcome to EMBO reports
LATEST: A balancing act: aneuploidy in focus. Four Reviews address this major health concern in a range of contexts, including cancer.
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upfront
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Mama Grizzly and the polar bears
Mis-reporting of climate science has undermined the judgement and integrity of scientists. Howy argues that scientists and journalists must communicate better to restore public confidence.
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Editorial: focus on aneuploidy
This issue of EMBO reports features four reviews that discuss aneuploidy and its consequences -important in cancer and fertility- from different viewpoints. This editorial sets the scene.
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featured scientific reports
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Niban regulates p53 stability via Nucleophosmin
The Lu lab reports that UV irradiation induces Niban phosphorylation by AKT, which increases the association of Niban with nucleophosmin and frees nucleophosmin from the MDM2 complex, resulting in p53 degradation and inhibition of apoptosis.
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review highlights
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A balancing act: aneuploidy in focus
Substantial efforts have been made to understand chromosomal aneuploidy, which causes mental retardation and spontaneous miscarriage, and is prevalent in most solid tumours and half of haematopoietic cancers.
This issue of EMBO reports highlights recent advances in this field through four Reviews. Rolf Jessberger analyzes the loss of accuracy of oocyte meiosis with age, and reviews by Holland & Cleveland, Pfau & Amon and Swanton & colleagues focus on aneuploidy in the context of cancer.
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science & society highlights
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To serve and protect research integrity
David Wright, the Director of the US Office of Research Integrity, discusses the causes and consequences of research misconduct and ways to address the problem.
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latest news
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The June cover
This month's cover is based on the latest Review Series, A balancing act: aneuploidy in focus.
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New Focus on Aneuploidy
EMBO reports presents a series of online focuses that bring together high quality published content on current and relevant themes. The latest focus is on Aneuploidy. Other focus topics include articles on Food, Stem Cells, Autophagy, Protein Modification, Convergence Research and MicroRNAs as well as our 10th Anniversary Editorial Collection. Why not take a look?
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Latest AOP Highlight
DeSUMOylating isopeptidase: a second class of SUMO protease
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top downloads
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CDK targeting of NBS1 promotes DNA-end resection, replication restart and homologous recombination
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Kinetic analysis reveals successive steps leading to miRNA-mediated silencing in mammalian cells
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Chromosomal instability and aneuploidy in cancer: from yeast to man
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Losing balance: the origin and impact of aneuploidy in cancer
scientific reports
review
science & society
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Other publications
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The EMBO Journal
The EMBO Journal is a print and online publication dedicated to providing a variety of complete and rapidly published articles in all areas of molecular biology. It is an influential and highly appreciated international journal run by scientists for scientists.
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Molecular Systems Biology
Molecular Systems Biology is an open access online only journal covering all aspects of the rapidly growing and interdisciplinary field of systems biology at the molecular levels.
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