1.
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ToxCast Phase I
Science and Technology
pesticide, Toxicology, ToxCast, pollutant, ...
Background: Chemical toxicity testing is being transformed by advances in biology and computer modeling, concerns over animal use and the thousands of environmental chemicals lacking toxicity data. EPA's ToxCast program aims to address these concerns by screening and prioritizing chemicals for potential human toxicity using in vitro assays and in silico approaches. Objectives: This project aims to evaluate the use of in vitro assays for understanding the types of molecular and pathway perturbations caused by environmental chemicals and to build initial prioritization models of in vivo toxicity. Methods: We tested 309 mostly pesticide active chemicals in 467 assays across 9 technologies, including high-throughput cell-free assays and cell-based assays in multiple human primary cells and cell lines, plus rat primary hepatocytes. Both individual and composite scores for effects on genes and pathways were analyzed. Results: Chemicals display a broad spectrum of activity at the molecular and pathway levels. Many expected interactions are seen, including endocrine and xenobiotic metabolism enzyme activity. Chemicals range in promiscuity across pathways, from no activity to affecting dozens of pathways. We find a statistically significant inverse association between the number of pathways perturbed by a chemical at low in vitro concentrations and the lowest in vivo dose at which a chemical causes toxicity. We also find associations between a small set in vitro assays and rodent liver lesion formation. Conclusions: This approach promises to provide meaningful data on the thousands of untested environmental chemicals, and to guide targeted testing of environmental contaminants.
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6 views
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2.
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TRI Explorer
Geography and Environment
inventory, pollutant, Toxics Release Inventory, ...
TRI Explorer provides powerful, flexible, user-friendly access to Toxics Release Inventory (TRI) data to help communities identify facilities and chemical disposal or other release patterns that may warrant further study and analysis. Combined with hazard and exposure information, the TRI Explorer can be a valuable tool for risk identification. The TRI is a centerpiece of the community right-to-know approach for environmental information mandated by the Emergency Planning and Community Right-to-Know Act (EPCRA) of 1986.
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3 views
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3.
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Web page with links to air quality and emissions data
Geography and Environment
pollutant, emission, federal data download, ...
A web page that describes and links to EPA systems for accessing and downloading ambient (outdoor) air quality and emissions data
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0 views
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4.
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Air Quality Forecast Guidance
Geography and Environment
particulates, health, quality, smoke, pollution, ...
NOAA's National Weather Service National Air Quality Forecast System (AQFS) Graphic Forecast displays (http://www.weather.gov/aq) are web based presentations of gridded forecast guidance originating from the National Centers for Environmental Prediction (NCEP). Ozone and smoke data are displayed for a domain covering contiguous United States, Alaska and Hawaii. Ozone is shown as 1-hour and 8-hour average concentrations(in parts per billion or ppb), and smoke concentration in 1-hour averages, updated twice daily. Fire locations are provided by the NOAA's Satellite and Information Service Hazard Mapping System. Additional information on air quailty can be found under EPA's AIRNow site. For further information, please visit NOAA's Air Resources Laboratory web site (http://www.arl.noaa.gov).
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1 view
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5.
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Toxics Release Inventory Chemical Hazard Information Profiles (TRI-CHIP) Dataset
Geography and Environment
TRI-CHIP, risk, inventory, TRI, IRIS, pollutant, ...
The Toxics Release Inventory (TRI) Chemical Hazard Information Profiles (TRI-CHIP) dataset contains hazard information about the chemicals reported in TRI. Users can use this XML-format dataset to create their own databases and hazard analyses of TRI chemicals. The hazard information is compiled from a series of authoritative sources including the Integrated Risk Information System (IRIS). The dataset is provided as a downloadable .zip file that when extracted provides XML files and schemas for the hazard information tables.
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10 views
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6.
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SITE COMPREHENSIVE LISTING (CERCLIS) (Superfund) - NPL Sites
Geography and Environment
Comprehensive Environmental Response Compensation ...
National Priorities List (NPL) Sites - The Comprehensive Environmental Response, Compensation and Liability Information System (CERCLIS) ("Superfund") Public Access Database contains a selected set of non-enforcement confidential information and is updated by the regions every 90 days. The data describes what has happened at Superfund sites prior to this quarter (updated quarterly). This database includes lists of involved parties (other Federal Agencies, states, and tribes), Human Exposure and Ground Water Migration, and Site Wide Ready for Reuse, Construction Completion, and Final Assessment Decision (GPRA-like measures) for fund lead sites. Other information that is included has been included only as a service to allow public evaluations utilizing this data. EPA does not have specific Data Quality Objectives for use of the data. Independent Quality Assessments may be made of this data by reviewing the QAPP
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6 views
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7.
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SITE COMPREHENSIVE LISTING (CERCLIS) (Superfund)
Geography and Environment
Comprehensive Environmental Response Compensation ...
The Comprehensive Environmental Response, Compensation and Liability Information System (CERCLIS) ("Superfund") Public Access Database contains a selected set of non-enforcement confidential information and is updated by the regions every 90 days. The data describes what has happened at Superfund sites prior to this quarter (updated quarterly). This database includes lists of involved parties (other Federal Agencies, states, and tribes), Human Exposure and Ground Water Migration, and Site Wide Ready for Reuse, Construction Completion, and Final Assessment Decision (GPRA-like measures) for fund lead sites. Other information that is included has been included only as a service to allow public evaluations utilizing this data. EPA does not have specific Data Quality Objectives for use of the data. Independent Quality Assessments may be made of this data by reviewing the Quality Assurance Action Plan (QAPP).
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4 views
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8.
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SITE COMPREHENSIVE LISTING (CERCLIS) (Superfund) - Responsible Parties at CERCLIS Sites
Geography and Environment
non-NPL, ...
Responsible Parties at CERCLIS Sites - The Comprehensive Environmental Response, Compensation and Liability Information System (CERCLIS) ("Superfund") Public Access Database contains a selected set of non-enforcement confidential information and is updated by the regions every 90 days. The data describes what has happened at Superfund sites prior to this quarter (updated quarterly). This database includes lists of involved parties (other Federal Agencies, states, and tribes), Human Exposure and Ground Water Migration, and Site Wide Ready for Reuse, Construction Completion, and Final Assessment Decision (GPRA-like measures) for fund lead sites. Other information that is included has been included only as a service to allow public evaluations utilizing this data. EPA does not have specific Data Quality Objectives for use of the data. Independent Quality Assessments may be made of this data by reviewing the Quality Assurance Action Plan (QAPP).
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4 views
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9.
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SITE COMPREHENSIVE LISTING (CERCLIS) (Superfund) - Non-NPL Sites
Geography and Environment
non-NPL, ...
Non-NPL Sites - The Comprehensive Environmental Response, Compensation and Liability Information System (CERCLIS) ("Superfund") Public Access Database contains a selected set of non-enforcement confidential information and is updated by the regions every 90 days. The data describes what has happened at Superfund sites prior to this quarter (updated quarterly). This database includes lists of involved parties (other Federal Agencies, states, and tribes), Human Exposure and Ground Water Migration, and Site Wide Ready for Reuse, Construction Completion, and Final Assessment Decision (GPRA-like measures) for fund lead sites. Other information that is included has been included only as a service to allow public evaluations utilizing this data. EPA does not have specific Data Quality Objectives for use of the data. Independent Quality Assessments may be made of this data by reviewing the Quality Assurance Action Plan (QAPP).
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2 views
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10.
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CERCLIS (Superfund) ASCII Text Format - CPAD Database
Geography and Environment
non-NPL, ...
The Comprehensive Environmental Response, Compensation and Liability Information System (CERCLIS) ("Superfund") Public Access Database (CPAD) contains a selected set of non-enforcement confidential information and is updated by the regions every 90 days. The data describes what has happened at Superfund sites prior to this quarter (updated quarterly). This database includes lists of involved parties (other Federal Agencies, states, and tribes), Human Exposure and Ground Water Migration, and Site Wide Ready for Reuse, Construction Completion, and Final Assessment Decision (GPRA-like measures) for fund lead sites. Other information that is included has been included only as a service to allow public evaluations utilizing this data. EPA does not have specific Data Quality Objectives for use of the data. Independent Quality Assessments may be made of this data by reviewing the Quality Assurance Project Plan (QAPP).
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2 views
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11.
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SITE COMPREHENSIVE LISTING (CERCLIS) - Contaminants at CERCLIS (Superfund) Sites
Geography and Environment
Comprehensive Environmental Response Compensation ...
Contaminants at Comprehensive Environmental Response, Compensation and Liability Information System (CERCLIS) ("Superfund") Sites - The CERCLIS Public Access Database contains a selected set of non-enforcement confidential information and is updated by the regions every 90 days. The data describes what has happened at Superfund sites prior to this quarter (updated quarterly). This database includes lists of involved parties (other Federal Agencies, states, and tribes), Human Exposure and Ground Water Migration, and Site Wide Ready for Reuse, Construction Completion, and Final Assessment Decision (GPRA-like measures) for fund lead sites. Other information that is included has been included only as a service to allow public evaluations utilizing this data. EPA does not have specific Data Quality Objectives for use of the data. Independent Quality Assessments may be made of this data by reviewing the Quality Assurance Action Plan (QAPP ).
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3 views
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12.
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ECOTOX Knowledgebase
Geography and Environment
Adverse Effects, Toxicology, Toxic Effects, ...
ECOTOX is the largest database compilation of ecotoxicity information in the world, providing data on the adverse effects of single chemical stressors to ecologically relevant aquatic and terrestrial species. The primary source of ECOTOX data is the peer-reviewed literature, resulting from comprehensive searches of the open literature followed by abstraction and review of data that meet minimum data quality requirements. ECOTOX also includes third-party data collections from U.S. EPA Program Offices, the U.S. Geologic Survey, Russia, and OECD member nations. Data are not interpreted during the coding process, representing the information on species, chemicals, test methods and toxicity results as presented by the author(s).
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11 views
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13.
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Power Plant Electricity Generation and Emissions
Energy and Utilities
power plants, environment, federal data download, ...
Comprehensive source of data on the environmental characteristics of almost all electric power generated in the United States
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6 views
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14.
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MyEnvironment Widget
Geography and Environment
environmental data, Envirofacts, toxic, facilities, ...
The MyEnvironment widget displays a variety of environmental information based on a user-specified area of interest
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6 views
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15.
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Aerometric Information Retrieval System (AIRS) Widget
Geography and Environment
environmental data, Envirofacts, pollution, ...
The Aerometric Information Retrieval System (AIRS) widget allows users to enter a specific location and retrieve facilities in the area of interest that produce air emissions as reported by the Aerometric Information Retrieval System (AIRS).
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1 view
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16.
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EPA Data Finder
Geography and Environment
USEPA, chemical, toxic, pollution, land, chemicals, ...
Data Finder is a tool to find EPA's data sources to help people access and understand environmental information. All of the data sources are available on the Internet and have been organized by topics such as air, water, and chemicals.
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19 views
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17.
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Chemical Data Access Tool
Geography and Environment
pollutant, chemical access tool, hpvis, chemicals, ...
This tool is intended to aid individuals interested in learning more about chemicals that are manufactured or imported into the United States. Health and safety information on these chemicals, primarily in the form of paper documents, are routinely submitted by industry (manufacturers or importers of chemicals) to EPA under the Toxic Substances Control Act (TSCA). EPA is in the process of converting these documents into electronic form and making non-confidential versions of these documents accessible through this tool. The tool enables users to conduct both full text and metadata searches of these documents, and presents these as *.pdf for viewing or downloading. The tool also queries existing EPA legacy database sources of chemical information and presents these data in a consistent format.
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8 views
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18.
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TOXMAP : online toxicology maps.
Health and Nutrition
TRI, Geographic Information System, ...
TOXMAP(r) is a Geographic Information System (GIS) that uses maps of the United States to help users visually explore data from the EPA's Toxics Release Inventory (TRI) and Superfund Programs. TOXMAP helps users create nationwide, regional, or local area maps showing where TRI chemicals are released on-site into the air, water, and ground. It also provides facility and release details, color-codes release amounts for a single year or year range, and aggregates release data over multiple years. Maps also show locations of Superfund National Priority List (NPL) sites, listing all chemical contaminants present at these sites.
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5 views
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19.
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Clean Air Markets 2007 Daily Emissions
Energy and Utilities
Air Quality, nitrogen oxides, carbon dioxide, ...
Daily emissions from entities regulated under Acid Rain and other "cap and trade " programs ... power plants and other facilities
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1 view
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20.
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Chesapeake Bay Program Water Quality Database
Geography and Environment
biology, salinity, indicators, toxic, biological, ...
The Chesapeake Information Management System (CIMS), designed in 1996, is an integrated, accessible information management system for the Chesapeake Bay Region. CIMS is an organized, distributed library of information and software tools designed to increase basin-wide public access to Chesapeake Bay information. The information delivered by CIMS includes technical and public information, educational material, environmental indicators, policy documents, and scientific data. Through the use of relational databases, web-based programming, and web-based GIS a large number of Internet resources have been established. These resources include multiple distributed on-line databases, on-demand graphing and mapping of environmental data, and geographic searching tools for environmental information. Baseline monitoring data, summarized data and environmental indicators that document ecosystem status and trends, confirm linkages between water quality, habitat quality and abundance, and the distribution and integrity of biological populations are also available. One of the major features of the CIMS network is the Chesapeake Bay Program's Data Hub, providing users access to a suite of long- term water quality and living resources databases. Chesapeake Bay mainstem and tidal tributary water quality, benthic macroinvertebrates, toxics, plankton, and fluorescence data can be obtained for a network of over 800 monitoring stations.
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23 views
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21.
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Clean Air Status and Trends Network (CASTNET): Ozone
Geography and Environment
public health, Ozone, environment, ...
8-hour daily maximum ozone concentrations as measured by the Clean Air Status and Trends Network (CASTNET)
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16 views
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22.
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1993 Toxics Release Inventory data for the state of California
Geography and Environment
TRI State Data, TRI Data, PBT, ...
Toxics Release Inventory Data. The Toxics Release Inventory (TRI) is a publicly available EPA database that contains information on toxic chemical releases and waste management activities reported annually by facilities in certain industries as well as federal facilities.
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163 views
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23.
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KMZ file of EPA Ambient Ozone Monitors
Geography and Environment
public health, ambient air, Ozone, environment, ...
A KMZ file with the location of all the EPA ambient ozone monitors with the ability to download data from within the description box.
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3 views
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24.
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Air Quality System (AQS) ambient observations: 2007 ozone
Geography and Environment
public health, ambient air, Ozone, environment, ...
Ambient ozone concentrations for 2007 from the national ambient air quality monitoring networks stored in the Air Quality System (AQS).
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2 views
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25.
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Web page with Air Quality System (AQS) ambient observation files
Geography and Environment
public health, Air Quality, ambient air, ...
Ambient concentrations of most requested pollutants from the national ambient air quality monitoring networks stored in the Air Quality System (AQS).
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2 views
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