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Research

Basic research interests include:

  • The regulation of cytokine gene expression
  • Age-related changes in protein structure and function
  • Atherosclerosis and oxidative stress
  • Chemotherapeutics
  • Molecular and immunological aspects of cancer biology and progession
  • Growth factors
  • Signal transduction
  • Apoptosis
  • Determination of enzyme mechanisms and other physical techniques by steady-state kinetics
  • The regulation of eukaryotic gene expression
  • Host response to respiratory infections
  • Antihelmintic drugs, parasite metabolism, enzymology and X-ray crystallography of parasite enzymes
  • Molecular immunology
  • Autoimmunity
  • Tumor immunology
  • Structure and function of the human chromosome
  • Vaccine development
  • Mechanism of muscle contraction
  • Cancer metastasis and angiogenesis
  • Cholesterol metabolism
  • Lipoprotein transport
  • Drug Delivery

Many research projects also involve faculty members from other basic science and clinical departments and institutes.

 

Current Research Activities