Fluorouracil This page contains brief information about fluorouracil and a collection of links to more information about the use of this drug, related research results, and ongoing clinical trials. US Brand Name(s): | ![](https://webarchive.library.unt.edu/web/20090829224556im_/http://www.cancer.gov/images/spacer.gif) | Adrucil | ![](https://webarchive.library.unt.edu/web/20090829224556im_/http://www.cancer.gov/images/spacer.gif) | | ![](https://webarchive.library.unt.edu/web/20090829224556im_/http://www.cancer.gov/images/spacer.gif) | Efudex | ![](https://webarchive.library.unt.edu/web/20090829224556im_/http://www.cancer.gov/images/spacer.gif) | | ![](https://webarchive.library.unt.edu/web/20090829224556im_/http://www.cancer.gov/images/spacer.gif) | Fluoroplex | ![](https://webarchive.library.unt.edu/web/20090829224556im_/http://www.cancer.gov/images/spacer.gif) | ![](https://webarchive.library.unt.edu/web/20090829224556im_/http://www.cancer.gov/images/spacer.gif) | FDA Approved: | ![](https://webarchive.library.unt.edu/web/20090829224556im_/http://www.cancer.gov/images/spacer.gif) | Yes |
Fluorouracil is approved by the Food and Drug Administration (FDA) for palliative treatment of the following:
Fluorouracil is approved to be used with other drugs to treat: Fluorouracil is also approved to be used by itself as a topical treatment for the following: Fluorouracil is also called "5-FU". In addition to the uses that have been approved by the FDA, fluorouracil is sometimes used alone or with other drugs to treat other types of cancer. Fluorouracil also continues to be studied in the treatment of many types of cancer. Information from the NCIDefinition from the NCI Drug Dictionary - Detailed scientific definition and other names for this drug.
Clinical Trial Results: 5-FU–Based Chemotherapy Cures Some Patients with Colon Cancer (02/03/2009) - Important clinical trial results for this drug, background information, and how the trial was done.
Clinical Trial Results: Chemotherapy Before Surgery May Increase Survival in Stomach Cancer (07/09/2007) - Important clinical trial results for this drug, background information, and how the trial was done.
Clinical Trial Results: Patients with Esophageal Cancer May Be Able to Avoid Surgery (04/16/2007) - Important clinical trial results for this drug, background information, and how the trial was done.
Clinical Trial Results: Chemotherapy Delays Recurrence of Liver Metastases from Colorectal Cancer (12/06/2006) - Important clinical trial results for this drug, background information, and how the trial was done.
Clinical Trial Results: Capecitabine an Alternative in Post-Surgery Treatment of Stage III Colon Cancer (07/27/2005) - Important clinical trial results for this drug, background information, and how the trial was done.
Clinical Trial Results: Docetaxel Combination Effective After Surgery for Node-Positive Breast Cancer (06/28/2005) - Important clinical trial results for this drug, background information, and how the trial was done.
Clinical Trial Results: Adding Docetaxel Improves Survival in Stomach Cancer (05/15/2005) - Important clinical trial results for this drug, background information, and how the trial was done.
Clinical Trial Results: Docetaxel Before Radiation Extends Survival in Patients with Head and Neck Cancer (06/05/2004) - Important clinical trial results for this drug, background information, and how the trial was done.
Information from the National Library of Medicine (NLM)
MedlinePlus Information on Fluorouracil - A lay language summary of important information about this drug that may include the following:
- warnings about this drug,
- what this drug is used for and how it is used,
- what you should tell your doctor before using this drug,
- what you should know about this drug before using it,
- other drugs that may interact with this drug, and
- possible side effects.
Drugs are often studied to find out if they can help treat or prevent conditions other than the ones they are approved for. This NLM patient information sheet applies only to approved uses of the drug. However, much of the information may also apply to unapproved uses that are being studied.
MedlinePlus Information on Topical Fluorouracil - A lay language summary of important information about this drug that may include the following:
- warnings about this drug,
- what this drug is used for and how it is used,
- what you should tell your doctor before using this drug,
- what you should know about this drug before using it,
- other drugs that may interact with this drug, and
- possible side effects.
Drugs are often studied to find out if they can help treat or prevent conditions other than the ones they are approved for. This NLM patient information sheet applies only to approved uses of the drug. However, much of the information may also apply to unapproved uses that are being studied. Clinical TrialsClinical Trials for Fluorouracil - Check for trials from NCI's PDQ Cancer Clinical Trials Registry now accepting patients.
Important: The drug information on this Web page is meant to be educational. It is not a substitute for medical advice. The information may not cover all possible uses, actions, interactions, or side effects of this drug, or precautions to be taken while using it. Please see your health care professional for more information about your specific medical condition and the use of this drug.
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