OriGene shRNA Recent Citations

RNA interference-mediated in vivo silencing of FasL as a strategy for the enhancement of DNA vaccine potency, Human Gene Therapy. August 2008, 19(8): 763-773 [sh-Luc(in vivo application)]

Suppression of Sproutys Has a Therapeutic Effect for a Mouse Model of Ischemia by Enhancing Angiogenesis, Koji Taniguchi, Ken-ichiro Sasaki, Kousuke Watari, Hideo Yasukawa, Tsutomu Imaizumi, Toranoshin Ayada, Fuyuki Okamoto, Takuma Ishizaki,Reiko Kato,Ri-ichiro Kohno,Hiroshi Kimura,Yasufumi Sato,Mayumi Ono,Yoshikazu Yonemitsu,and Akihiko Yoshimura, PLoS ONE. 2009; 4(5): e5467 [Spry4(in vivo application)]

MicroRNA-98 and let-7 Confer Cholangiocyte Expression of Cytokine-Inducible Src Homology 2-Containing Protein in Response to Microbial Challenge, J. Immunol., Aug 2009; 183: 1617 - 1624 [CISH]

[6]-Gingerol Suppresses Colon Cancer Growth by Targeting Leukotriene A4 Hydrolase, Cancer Res., Jul 2009; 69: 5584 - 5591 [LTA4H]

Breast Cancer Migration and Invasion Depend on Proteasome Degradation of Regulator of G-Protein Signaling 4, Cancer Res., Jul 2009; 69: 5743 - 5751. [RGS4]

DNA damage-induced phosphorylation of TRF2 is required for the fast pathway of DNA double-strand break repair, Mol. Cell. Biol., Jul 2009; 29: 3597 - 3604 [TRF2]

Dual regulation of lysophosphatidic acid (LPA1) receptor signalling by Ral and GRK, Cellular Signalling, Volume 21, Issue 7, July 2009, Pages 1207-1217 [RALa]

All Citations click here

Exact-shRNA: Custom shRNA service

Exact-shRNA is an shRNA service for the special needs outside our pre-designed shRNA products. Examples are

shRNA targeting species other than Human, Mouse or Rat
Integrate an effective siRNA oligo sequence into an shRNA vector
Isoform-specific knock down
Have shRNA constructs that target multiple species
Reproduce a published result where shRNA sequence is available/disclosed

There are two modes of service with Exact-shRNA:

Self-design: Customers specify the short hairpin sequences (stem and loop) and OriGene constructs the vector. This is targeted to researchers who have gained knowledge of the effective target sequence, either from previous research or from published work. Up to 4 constructs are allowed for each project. Additional constructs can be submitted as a new project.
OriGene-design: Customers define the transcript sequence(s) and OriGene designs the shRNA (stem and loop) using our proprietary algorithm. Four constructs will be designed whenever possible.

Click here to fill out the Exact-shRNA Request Form. When placing an order, just refer to the catalog number on the request form.

If you would like some assistance in the design of your shRNA constructs, we have experienced molecular biologists in our technical support team ready to help. Contact the Exact-shRNA team at 301.340.3188 option 2.

Useful Links

Related Products: