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OriGene proteins in recent publications

Fully functional proteins purified from transient TrueORF cDNA clone transfections.  Researchers purified GEN1 protein using anti-FLAG M2 affinity column and determined it resolved Holliday junction X0 efficiently in vitro, thus confirming GEN1 is human Holliday junction resolvase.

Identification of Holliday junction resolvases from humans and yeast, Stephen C. Y. Ip, Ulrich Rass, Miguel G. Blanco, Helen R. Flynn, J. Mark Skehel, Stephen C. West, Nature 456, 357 - 361 (20 Nov 2008), doi: 10.1038/nature07470,


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5,000 Purified Human Proteins from HEK293 Cells

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Powered by extensive collection of TrueORF human cDNA clones, OriGene now offers >5,000 full length human proteins expressed in HEK293 cells and purified with affinity column.

  • The broadest offering of human proteins produced in human cells
  • Optimal preservation of protein structure, post-translational modifications and functions
  • >80% purity through affinity purification
  • Options for large scale production available.

Applications

  • Native antigens for optimized antibody production
  • Positive controls in antibody assays
  • Standards in ELISA and other assays
  • Protein-protein interaction
  • In vitro biochemical assays and cell-based functional assays

Comparison of different protein expression systems
  Mammalian Yeast Insect cells E. coli
Protein folding and purification Optimal Poor Low Poor
Post-translational processing Yes Low Low No
Authenticity & Bioactivity Native and Active Poor Poor Very Poor

Catalog # Description Pricing
TPxxxxxx Affinity purified full length human protein expressed in human HEK293 cells, 20 ug in liquid form $680

Search for your proteins, typing protein name, symbol, accession number or keyword in the box below, and select Proteins
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Technical Support
Our scientists will answer your technical questions from 9AM to 7PM ET. Call 1-888-267-4436
Custom protein purification service
In addition to full length proteins expressed in human HEK293 cells, OriGene offers custom protein expression and purification service to your specific needs, including protein domains, different expression tags, expression host, etc. Please use this custom protein service request form.

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