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Birth Defects Home > Birth Defects Topics > Gastroschisis
Gastroschisis
Pronounced gas-troh-skee-sis

Gastroschisis is a birth defect in which a portion of an infant's intestines protrude out of the body through a small hole in the body wall beside the umbilical cord. The body wall defect can be small or large and other organs such as the liver can be involved. 

To learn more about gastroschisis click on one of the following links or scroll down the page.

What We Know About Gastroschisis

  • How often does gastroschisis occur?
  • What problems do children with gastroschisis have?

What We Still Do Not Know About Gastroschisis

  • What causes gastroschisis?
  • Can gastroschisis be prevented?

Resources for Families and Individuals Affected by Gastroschisis

 

What We Know About Gastroschisis

How often does gastroschisis occur?
CDC estimates that each year about 1,500 babies in the United States are born with gastroschisis (1). In other words, about 1 out of every 2,500 babies born in the United States each year will have gastroschisis.

What problems do children with gastroschisis have?
Infants and children with gastroschisis usually are expected to have some problems. These include problems of movement of digested food through the stomach and intestines, and absorption of nutrients. This is due to the intestine’s being uncovered and irritated by the amniotic fluid. In addition, the misplaced organs can make it difficult for the baby’s lungs to expand, which can cause breathing problems. Sometimes death of the bowel is a complication.

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What We Still Do Not Know About Gastroschisis

What causes gastroschisis?
Gastroschisis occurs during pregnancy when the muscles of the wall of the baby’s abdomen do not form correctly. Some scientists think that genetics or an environmental exposure during pregnancy can cause gastroschisis, but the exact cause is still unknown.
We at CDC work with many other researchers to study risk factors that can increase the chance of having a baby with gastroschisis. Following are examples of what our research has found:

  • Teenage mothers are more likely to have a baby with gastroschisis than older mothers, and White teenagers have higher rates than Black or African-American teenagers (2).
  • Mothers eating a high-fat and high-cholesterol diet before they get pregnant can increase their risk for having a baby with gastroschisis, although more research is needed on this topic (3).

Can gastroschisis be prevented?
Currently, there is no known way to prevent gastroschisis. Even so, mothers can take steps before and during pregnancy to have a healthy pregnancy. These steps include taking a daily multivitamin with folic acid (400 micrograms), not smoking, and not drinking alcohol during pregnancy. 

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Resources for Families and Individuals Affected by Gastroschisis

Fetal Treatment Center at UCSF

Medline


References

  1. Canfield MA, Honein MA, Yuskiv N, Xing J, Mai CT, Collins JS, et al. National estimates and race/ethnic-specific variation of selected birth defects in the United States, 1999-2001. Birth Defects Res Part A Clin Mol Teratol. 2006;76(11):747–56.
  2. Williams LJ, Kucik JE, Alverson CJ, Olney RS, Correa A. Epidemiology of gastroschisis in metropolitan Atlanta, 1968 through 2000. Birth Defects Res A. 2005; 73:177-83.
  3. Siega-Riz AM, Olshan AF, Werler MW, Moore CA, and the National Birth Defects Prevention Study. Fat intake and the risk of gastroschisis. Birth Defects Res A. 2006; 76(11):241-45.

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Date: March 11, 2009
Content source: National Center on Birth Defects and Developmental Disabilities

 

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