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Division of Allergy, Immunology, and Transplantation (DAIT)

Gene Knockout/Transgenic MiceNIAID Exchange Program

To foster increased availability to the scientific community of immunologically-related, gene-targeted mouse strains, the National Institute of Allergy and Infectious Diseases (NIAID) has instituted a special partnership with Taconic Farms, Inc., called the NIAID Exchange Program. The costs of this Program are partially underwritten by NIAID funds to provide ready access to emerging mouse models. The strains chosen for the Exchange Program are selected by the NIAID Mouse Repository Committee based on expected interest to the scientific community and degree of genetic standardization and phenotypic characterization. The 21 strains currently available are:

  • [KO]gc chain and [KO]Rag2, C57BL/6xC57BL/10SgSnAi bkg
  • [KO]Nos2, C57BL/6Ai bkg C57BL/6-[KO]iNOSN9
  • B10.D2-[TG] TCR DO11.10-[KO]RAG2 N10,N2
  • B10.A-[TG]5CC7-1-[KO]RAG2 N12
  • C57BL/10-[KO]gc-[KO]RAG2 N9, N1
  • C57BL/10-[TG] TCR P14 LCMV-[KO]RAG2 N11
  • C57BL/6-[TG]MHC hu DR-4 a1b1-[KO]Abb
  • BALB/c-IL4Ra[KO]
  • B6-CD4-Cre
  • B6-lck Cre
  • B6-Flt3[KO]
  • B6-IL15[KO]
  • BALB/c-[TG]DO11.10-[KO]RAG2
  • B7-[TG] OT_I-[KO]RAG1
  • B6-[KO]PHOX
  • B10-[TG] P14 LCMV-[KO] TCRa
  • B6-[KO] CCR1
  • B6-[KO]Db-[KO] Kb
  • B6-[KO] Kb
  • B6-[KO] Db
  • B10.D2
  • B6.SJL

For more information, email Taconic or call 518-537-6208, or access the Taconic Emerging Models Site.

News Releases

NIAID Media Availability: Still Searching for Asthma Predictors
Aug. 10, 2009

NIH Media Availability: Found: A Gene That May Play a Role in Type 1 Diabetes
Aug. 9, 2009

Joint Statement on Food Allergy Awareness Week 
May 11, 2009

Highlights

Government Links

HHS Initiatives and Projects on Organ Donation

Decision: Donation A School Program That Gives the Gift of Life

Food Allergy Clinical Guidelines

Non-government Links

Task Force Report on Allergic Disorders: Promoting Best Practice (The Allergy Report)


News Releases

NIAID Media Availability: Still Searching for Asthma Predictors
Aug. 10, 2009

NIH Media Availability: Found: A Gene That May Play a Role in Type 1 Diabetes
Aug. 9, 2009

Joint Statement on Food Allergy Awareness Week 
May 11, 2009

Highlights

Government Links

HHS Initiatives and Projects on Organ Donation

Decision: Donation A School Program That Gives the Gift of Life

Food Allergy Clinical Guidelines

Non-government Links

Task Force Report on Allergic Disorders: Promoting Best Practice (The Allergy Report)