Protein Lounge organizes gene/protein data into a single gateway, improving access and supporting greater understanding of systems biology.

Ten Protein Lounge databases are available to NIH staff¹:

• Biochemical Compound Database ("contains text and graphics describing important molecules commonly involved in cellular signaling, biosynthesis and metabolism"), 
• Disease Genes Database ("an accumulation of hundreds of diseases linked to the genes which are responsible for causing the disease"), 
• GPCR Database (G Protein-Coupled Receptors; "includes a list of thousands of membrane proteins that modulate sensory perception, chemotaxis, neurotransmission, cell communication, and many other vital physiological events"),
• Kinase-Phosphatase Database ("a list of all protein kinases and protein phosphatases organized with their substrates"),
• Pathway Database ("An extensive database of hundreds of protein signaling pathways in many organisms"),
• Peptide-Antigen Database ("contains antigenic peptide targets against all known protein sequences throughout a variety of organisms"),
• Protein Database ("contains datasheets, extensive reviews, disease relation, publications, related members, and sequence information"),
• Protein Interaction Database ("allows one to search for a protein, then view all of the other proteins which it activates, inhibits or binds to"),
• siRNA Database ("contains pregenerated statistically validated siRNA targets against ALL known genes of all major research organisms, including Human, Mouse, Rat, Fly, Yeast, Worm, Plant and more"), and
• Transcription Factor Database ("Complete database of transcription factors throughout variety species, organized by their DNA binding sequences, binding elements, and cell expression").

Protein Lounge also provides online research tools:

• Clean Compare ("allows you to compare DNA and protein sequences"),
• Clone Easy ("easiest and most efficient method for PCR cloning online . . . choose from a library of cloning vectors and enzymes"),
• Easy siRNA ("an efficient method of finding siRNA targets and cloning them online . . . based on the Tuschl algorithm to generate siRNA targets"),
• Lab Book ("allows you to store your experiments in your personal secure online Lab Book for viewing from any location"),
• Pathway Builder Tool ("a desktop application, which offers you the ultimate freedom to make your own pathways using premade membranes, organelles, proteins and other necessary pathway structures"),
• Peptide Antigen Finder ("finds the best antigenic peptides of a protein sequence"), 
• Protein Hydroplotter ("allows for the viewing of hydrophilic and hydrophobic regions of a protein sequence"), and
• Protein Vision ("an online 3D protein structure visualization tool").

To access Protein Lounge, go to the NIH Library Databases webpage
and click the "Protein Lounge" entry.

For assistance using Protein Lounge,
contact Medha Bhagwat (bhagwat@mail.nih.gov),
NIH Library specialist in bioinformatics. 



Protein Lounge Homepage 

Webpage Created: May 12, 2009

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