Department: Biochemistry and Molecular Biology
Interest: Regulation of smooth muscle myosins by phosphorylation and dephosphorylation. I am also interested in the interaction between myosin and actin, myosin light chain kinase and phosphatase.
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Hemophilia A is a recessive bleeding disorder that has been treated with fresh frozen plasma, with regular treatments requred through the life of the patient. Treating hemophilia while in the uterus would enable correction prior to disease onset, allowing for the birth of a healthy baby. Thus, the overall goals are to establish a clinically relevant large animal model for hemophilia A and to subsequently use this model to evaluate the efficacy of in utero stem cell transplantation for treating hemophilia. Read More...
Graca Almeida-Porada, Department of Animal Biotechnology
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