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August 3, 2009

Photo of a finger-prick test for diabetes.Intensive Glucose Control Reduces Complications of Type 1 Diabetes
Near-normal control of glucose beginning as soon as possible after diagnosis greatly improves the long-term prognosis of type 1 diabetes, a new study found.
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Photo of an arm in a blood pressure cuff.Gene Variants Linked to Blood Pressure in African-Americans
Scientists have identified several genetic variants associated with blood pressure in African-Americans. The results of the new study offer potential clues to treating and preventing chronic high blood pressure, or hypertension.
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Computer graphic of antibodies binding to antigens.Genetic Switch Discovered for Disease-Fighting Antibodies
Scientists have identified 2 proteins that regulate the production of antibodies that fight disease-causing viruses and other pathogens. The findings have potential applications both for vaccine development and for treating autoimmune diseases.
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July 27, 2009

Image of a long, glowing flatworm.Scientists Decode Genomes of Deadly Parasitic Flatworms
Scientists have sequenced the complete genomes of 2 flatworms that cause schistosomiasis, a devastating tropical disease. The accomplishment provides an invaluable resource for developing new tools to treat the disease.
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Photo of a dachshund. Gene Insertion Underlies Origin of Dogs With Short Legs
A single evolutionary event is responsible for the short, curved legs that characterize certain dog breeds, according to a new study. The unexpected discovery provides clues about how physical differences may arise within species.
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Cluster of round rotavirus particles.Rotavirus Vaccines Shift Course of Diarrhea-Causing Disease
New vaccines can prevent or temper epidemics of a leading childhood diarrhea-causing disease, help protect the unvaccinated and raise the age at which the infection first appears in children, researchers reported.
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July 13, 2009

Electron micrograph image of an influenza virus.New Insights Into Novel H1N1
This spring, a new influenza, or flu, virus began causing illness in people around the world. Several new studies have revealed where the virus came from and given insight into how dangerous it might become.
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Molecular model of DNA. Common Gene Variants Implicated in Schizophrenia
Three international research teams have detected many tiny and common gene variations that together could account for at least one-third of the genetic risk for schizophrenia.
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Illustation of an alcohol molecule bound to a protein.Alcohol’s Site of Action Revealed
People have used alcohol for thousands of years for its pleasant and intoxicating effects. A new study finally provides an explanation for how alcohol produces these effects in the brain. The breakthrough could lead to new treatments for alcohol abuse and dependence.
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June 29, 2009

Photo of grey blotch obscuring view of 2 children.Targeting Age-Related Macular Degeneration
Researchers have identified a key molecular player in a type of age-related macular degeneration. The discovery may lead to better methods of early detection and treatment for this leading cause of blindness.
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Electron micrograph of a cell packed with round granules.A Broader Role for Amyloids
Amyloids are best known for their role in diseases such as Alzheimer’s. A new study finds that amyloids may also have a normal biological function.
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Image of skin tissue shows clusters of green cells linked to red nerve fibers.Merkel Cells Give You a Light Touch
If you can feel the softness of silk or the fuzziness of a peach, you can thank your Merkel cells, scientists say. A new study confirms what researchers have long suspected—that cells in the skin called Merkel cells are essential to the sense of light touch.
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June 22, 2009

Photo of a man.Touted "Depression Risk Gene" May Not Add to Risk After All
A gene variation long thought to increase a person's risk for major depression when paired with stressful life events may actually have no effect, according to a new analysis. The result challenges a common approach to studying depression risk factors.
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Photo of  two young boys.Prevention Program Reduces Problem Behaviors in Fifth Graders
A new study found that elementary school children in a character development program were more likely to steer clear of substance abuse, violent behavior or sexual activity by fifth grade than those who weren’t offered the program.
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Image of yellow dots in red brain cell.Scientists Identify Culprit in Huntington's Disease
Scientists have solved why a faulty protein accumulates in cells throughout the body in people with Huntington’s disease, but only kills certain brain cells. It has an accomplice. The discovery provides a potential target to treat or slow the progression of Huntington's.
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June 15, 2009

Photo of an older man and a physician.Treatment Options for Those with Diabetes and Heart Disease
For most patients with diabetes and stable heart disease, intensive drug therapy is as effective as prompt surgery in preventing death, heart attack and stroke, according to a large clinical study.
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Image of human brain tissue with Creutzfeldt-Jakob disease.Researchers Discover How Prion Protein Damages Brain Cells
Scientists have gained a major insight into how the rogue protein responsible for mad cow disease and related neurological illnesses destroys healthy brain tissue.
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Illustration of an immune attack.Common Diabetes Drug Boosts Immune Memory
In a new mouse study, researchers were able to boost the immune system’s memory by using the anti-diabetic drug metformin. The unexpected finding could transform strategies for vaccine development.
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NIH Research Matters is a review of NIH research from the Office of Communications and Public Liaison, Office of the Director, National Institutes of Health.

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NIH Research Matters
Harrison Wein, Ph.D., Editor
Vicki Contie, Assistant Editor
National Institutes of Health
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This page was last updated August 3, 2009 .
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