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Article series: Study designsArticle series: Non-coding RNAArticle series: Translational geneticsEric L. Greer & Yang Shi
2010 Thomson Reuters Impact Factor 32.745(*Source of Impact Factor data)
Next issue date: 18 May 2012
Article Series: Study designs 
Mark Yandell & Daniel Ence
Although genome sequencing is becoming routine, genome annotation is becoming increasingly challenging. The authors provide an overview of the steps and software tools that are available for annotating eukaryotic genomes, and describe the best practices for sharing, quality checking and updating the annotation.
Article Series: Non-coding RNA 
Colin C. Pritchard, Heather H. Cheng & Muneesh Tewari
Owing to the important role of microRNAs in gene regulation, profiling repertoires of expressed microRNAs can be informative in basic research and clinical settings. This Review describes the methods that are available for microRNA profiling and considerations for choosing among analytical options.
Article Series: Study designs 
Sarah K. Volkman, Daniel E. Neafsey, Stephen F. Schaffner, Daniel J. Park & Dyann F. Wirth
This Review describes how genome-wide analyses have provided various insights into the most lethal malarial parasite, Plasmodium falciparum, including determinants of antimalarial drug resistance. The authors also propose how genetic tools can be refined to monitor future therapeutic interventions.
Eric L. Greer & Yang Shi
This Review provides a broad overview of the regulation of and by histone methylation. A balance between dynamism and stability is highlighted by links to disease and ageing, and current studies are exploring these histone marks in the context of inheritance.
Jane Kaye, Liam Curren, Nick Anderson, Kelly Edwards, Stephanie M. Fullerton, Nadja Kanellopoulou, David Lund, Daniel G. MacArthur, Deborah Mascalzoni, James Shepherd, Patrick L. Taylor, Sharon F. Terry & Stefan F. Winter
Participant-centred initiatives use social media technologies to allow long-term interactive partnerships to be established between study participants and researchers. These varied initiatives improve research governance and quality and give participants greater knowledge of and control over how their data are used.
Selected articles from the Nature Publishing Group on key current topics.
A special series of articles that explores a specific theme and that are published consecutively over a period of time.
A calendar of forthcoming meetings and workshops from across the field of genetics and genomics.
A poster provides a visual overview of a timely topic in genetics and can be viewed online as a high-resolution PDF.
The principles of RNAi are introduced in this free, 3D animation featuring small interfering RNAs (siRNAs) and microRNAs (miRNAs). Further information about RNAi is provided in an accompanying slideshow.
Animation by Arkitek Studios; advised by Craig C. Mello; sponsored by Thermo Scientific.
The articles in this series discuss insights into the biology of non-coding RNAs of all sizes in a wide range of organisms.
Provides an overview of the tools that have been developed to understand the functions of small RNAs and, conversely, the use of small RNAs as tools.
Produced with support from Thermo Scientific.
Describes the innovative ways in which the de novo engineering of genetic circuits, biological modules and synthetic pathways are being applied to address crucial medical and environmental problems.
With support from: 'OriGene Technologies and its wholly owned subsidiary, Blue Heron Biotechnology'
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2010 Journal Citation Report (Thomson Reuters, 2011)
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University of California, Irvine
Institut Pasteur
CSIRO (Commonwealth Scientific Research & Industrial Research Organisation)
Medical Research Council
Medical College of Wisconsin
16 April 2012 — 25 April 2012 Montevideo, Uruguay
24 July 2012 — 26 July 2012 Boston, United States
This Challenge is seeking a theoretical design of an “early warning” sensor for blood vessels in th…
The Seeker is looking for animal models of back pain.
This is a Reduction-to-Practice Challenge t…
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