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Software and Users' Manuals
Updates will be posted here periodically. It is the responsibility of the user to verify that the latest version of the software is being used.
Please also refer to the Guidance page for technical reports, guidance documents, and short sheets related to the use of the IEUBK and the ALM.
You will need Adobe® Acrobat Reader, available as a free download, to view some of the files on this page. See EPA's PDF page to learn more about PDF, and for a link to the free Acrobat Reader.
Bound hard copies of the 1994 IEUBK Model (version 0.99d) documentation can be purchased from the
National Technical Information Service (NTIS).
Download the IEUBK...
- Windows® version 1.0, build 264
- User's Guide
- Guidance Manual
- Technical Support Document
- Reference Manual
- System Requirements and Design document
Download the Adult Lead Methodology (ALM)...
Integrated Exposure Uptake Biokinetic Model for Lead in Children, Windows®
version (IEUBKwin v1.0 build 264)
(August, 2007) 32-bit version
This is the Windows®-based version of the IEUBK model (IEUBKwin v1.0 build 264).
Download Integrated Exposure Uptake Biokinetic Model for Lead in Children, Windows® version (IEUBKwin v1.0 build 264) (size: 7.56 MB)
To extract the model, save the self-executing file to a directory of your choice, then run the file to perform the setup. To run the model, click on the executable model file ieubkwin264.exe).
This build was created to update the links to the EPA web site.
Please visit the IEUBK Model Frequent Questions page for:
Answers to frequent questions on the IEUBK model.
Recent Food and Drug Administration (FDA) dietary lead in food data available for download (in SVD file format) into the IEUBK model.
User's Guide for the Integrated Exposure Uptake Biokinetic Model for Lead in Children
(IEUBK) Windows® 32-bit version
[EPA 9285.7-42] (Updated May 2007)
This is intended to serve as an instructional guide for users of IEUBKwin. It provides the basics needed for accurate application and interpretation of the model, including how to install and run the model, model inputs and output, model analysis, interpretation of results, minimum requirements for risk assessment application, and example scenarios. Users of the model can refer to the IEUBK Guidance Manual (U.S. EPA, 1994) for supplemental information concerning the parameters and correct application of IEUBKwin.
- User's Guide for the Integrated Exposure Uptake Biokinetic Model for Lead in Children (IEUBK) Windows® 32-bit version (PDF) (59 pp, 621K)
Guidance Manual for the Integrated Exposure Uptake Biokinetic Model for Lead in
Children
[NTIS #PB93-963510, EPA 9285.7-15-1] (February 1994)
This document concisely describes key features of the conceptual underpinnings of the IEUBK model, its evolution and development, its capabilities, and its limitations. The manual also provides guidance on the use of the model as a risk assessment tool.
The Guidance Manual for the Integrated Exposure Uptake Biokinetic Model for Lead in Children:
- Introductory Materials (PDF) (title page, TOC, glossary of terms) (268 pp, 164K)
- Chapter 1 (PDF) (29 pp, 190K)
- Chapter 2 (PDF) (50 pp, 947K)
- Chapter 3 (PDF) (13 pp, 238K)
- Chapter 4 (PDF) (67 pp, 422K)
- Chapter 5 (PDF) (32 pp, 154K)
- Chapter 6 (PDF) (11 pp, 63K)
- Appendix A (PDF) (16 pp, 167K)
- Appendix B (PDF) (5 pp, 30K)
Technical Support Document for the Integrated Exposure Uptake Biokinetic Model for Lead in Children (v0.99d)
[NTIS #PB94-963505, EPA 9285.7-22] (December 1994)
This document provides a detailed description of the equations and parameters used in the IEUBK model. It is a companion to the IEUBK Model Guidance Manual.
- Technical Support Document for the Integrated Exposure Uptake Biokinetic Model for Lead in Children (v0.99d) (PDF) (114 pp, 596K)
Reference Manual for the Integrated Exposure Uptake Biokinetic Model for Lead in Children (IEUBK) Windows®
32-bit version
[EPA 9285.7-44] (May 2002)
This document is intended as a quick introduction to IEUBKwin for users already familiar with the DOS version (0.99d). It describes the changes made to the model since the release of the DOS version (0.99d) in 1994. A general overview of the IEUBK model, a synopsis of the types of guidance documentation available for the IEUBK model (including directives, software documentation, short sheets, and fact sheets), and points of contact for additional information are all provided here.
System Requirements and Design for the Integrated Exposure Uptake Biokinetic Model for Lead in Children (IEUBK)
Windows® 32-bit version
[EPA 9285.7-43] (Updated May 2007)
This document is an all-inclusive synopsis of the requirements for the development of the IEUBK model. It documents the design and implementation of the converted program, and is intended as a reference which can be used in the future for model enhancement or modification. The requirements portion of this document describes the parameters and equations that are used in the DOS version (0.99d) of the model. The design portion describes the structure and details of the design of the model as converted from DOS to a Windows® program.
- System Requirements and Design for the Integrated Exposure Uptake Biokinetic Model for Lead in Children (IEUBK) Windows® 32-bit version (PDF) (131 pp, 2.8MB)
- Appendix A (PDF) (25 pp, 277K)
- Appendix B (PDF) (17 pp, 609K)
- Appendix C (PDF) (36 pp, 796K)
- Appendix D (PDF) (14 pp, 57K)
Recommendations of the Technical Review Workgroup for Lead for an Approach to Assessing Risks Associated with Adult Exposures
to Lead in Soil
[EPA-540-R-03-001, OSWER Dir #9285.7-54] December 1996 (January 2003) -- The Adult Lead Methodology (ALM)
Note: This January 2003 document does not incorporate the Third National Health and Nutrition Examination Survey (NHANES) recommendations of the TRW. Baseline blood lead concentration (PbB) and geometric standard deviation (GSD) values for the ALM should be input into the ALM based on the information presented in the NHANES report, available from the Guidance page.
This document describes a methodology for assessing risks associated with non-residential adult exposures to lead in soil. The methodology focuses on estimating fetal blood lead concentration in women exposed to lead-contaminated soils. This approach also provides tools that can be used for evaluating risks of elevated blood lead concentrations among exposed adults. Based on the TRW's analysis of the data collected in the completed NHANES III survey (Phases 1 and 2), updated ranges for the baseline adult blood lead concentration (PbB) and GSDi adult parameters in the EPA Adult Lead Methodology (ALM)have been included in the spreadsheets. Although the use of these updated ranges in the ALM would not appreciably change preliminary remediation goals (PRGs) calculated with the methodology, it is recommended that data from both phases of NHANES III be used in all PbB analyses; this is consistent with Centers for Disease Control (CDC) recommendations.
Adult Lead Methodology (ALM) (PDF) (55 pp, 702K)
NHANES III Analysis (PDF) (28 pp, 479K)
ALM spreadsheet (MS Excel) (Calculation of PRGs; Appendix B of ALM document) (4 pp, 55K)
Review of Adult Lead Models: Evaluation of Models for Assessing Human Health Risks Associated with Lead Exposures at
Non-Residential Areas of Superfund and Other Hazardous Waste Sites
[OSWER Dir #9285.7-46] August 2001 -- The ALM Review Report
This report reviews the Adult Lead Methodology (ALM), as well as other modeling approaches, and their potential applicability to assessing non-residential lead exposures and risks.