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Sponsored by: |
National Taiwan University Hospital |
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Information provided by: | National Taiwan University Hospital |
ClinicalTrials.gov Identifier: | NCT00746304 |
To investigate long-term treatment outcomes of patients receiving botulinum toxin A therapy for infantile and acquired esotropia.
Condition |
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Esotropia |
Study Type: | Observational |
Study Design: | Cohort, Retrospective |
Official Title: | Long-Term Outcomes in the Treatment of Infantile and Acquired Esotropia With Botulinum Toxin |
Enrollment: | 164 |
Study Start Date: | September 2007 |
Study Completion Date: | December 2007 |
Primary Completion Date: | October 2007 (Final data collection date for primary outcome measure) |
Groups/Cohorts |
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1
infantile esotropia
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2
acquired esotropia
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Participants: 164 patients with infantile esotropia and 89 patients with acquired esotropia.
Methods: Patients were injected with botulinum toxin into two medial rectus muscles and followed from 1992 to 2005. Patients were evaluated at 1 week, 2, 6 and 12 months, and then yearly post-injection.
Main Outcome Measures: Degree of motor alignment, recurrence rate, incidence of stereopsis, and dissociated vertical deviation along with complications.
Ages Eligible for Study: | up to 5 Years |
Genders Eligible for Study: | Both |
Accepts Healthy Volunteers: | No |
Sampling Method: | Non-Probability Sample |
A total of 373 patients with strabismus were treated with botulinum toxin injection by a single surgeon (AH Wang) at the Department of Ophthalmology, National Taiwan University Hospital, Taipei, Taiwan from 1992 to 2005.
Inclusion Criteria:
Exclusion Criteria:
Taiwan | |
National Taiwan University Hospital | |
Taipei, Taiwan, 100 |
Principal Investigator: | Tzu-Hsun Tsai, MD | National Taiwan University Hospital |
Responsible Party: | National Taiwan University Hospital ( Tsai Tzu-Hsun ) |
Study ID Numbers: | 200709002R |
Study First Received: | August 31, 2008 |
Last Updated: | August 31, 2008 |
ClinicalTrials.gov Identifier: | NCT00746304 |
Health Authority: | Taiwan: Department of Health |
botulinum esotropia |
Esotropia Ocular Motility Disorders Motor neuro-ophthalmic disorders Botulinum Toxins |
Eye Diseases Strabismus Ocular motility disorders |
Anti-Dyskinesia Agents Therapeutic Uses Nervous System Diseases |
Cranial Nerve Diseases Central Nervous System Agents Pharmacologic Actions |