![](https://webarchive.library.unt.edu/web/20090513042613im_/http://www.cancer.gov/images/spacer.gif) |
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![](https://webarchive.library.unt.edu/web/20090513042613im_/http://www.cancer.gov/images/spacer.gif)
recombinant tumor necrosis factor family protein A recombinant therapeutic agent which is chemically identical to or similar to one of a number of endogenous tumor necrosis factor (TNF) proteins. TNF family cytokines bind to and activate specific cell-surface receptors, thereby mediating inflammatory processes, cell proliferation, immunity, angiogenesis, and tumor cell cytotoxicity. One primary antitumor effect of TNFs involves stimulation of T cell-mediated antitumor cytotoxicity. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
![](https://webarchive.library.unt.edu/web/20090513042613im_/http://www.cancer.gov/images/spacer.gif)
Synonyms: | ![](https://webarchive.library.unt.edu/web/20090513042613im_/http://www.cancer.gov/images/spacer.gif) | tumor necrosis factor Tumor Necrosis Factor Family Protein | | ![](https://webarchive.library.unt.edu/web/20090513042613im_/http://www.cancer.gov/images/spacer.gif) | Acronym: | ![](https://webarchive.library.unt.edu/web/20090513042613im_/http://www.cancer.gov/images/spacer.gif) | TNF | | ![](https://webarchive.library.unt.edu/web/20090513042613im_/http://www.cancer.gov/images/spacer.gif) |
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