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c-Met inhibitor JNJ-38877605 An orally bioavailable, small-molecule receptor tyrosine kinase inhibitor with potential antineoplastic activity. c-Met inhibitor JNJ-38877605 selectively inhibits c-Met (mesenchymal-epithelial transition), a receptor tyrosine kinase (RTK) involved in cancer cell survival and invasiveness, and tumor angiogenesis.
c-Met is also known as hepatocyte growth factor receptor (HGFR). Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
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Code name: | ![](https://webarchive.library.unt.edu/web/20090509210430im_/http://www.cancer.gov/images/spacer.gif) | JNJ-38877605 | | ![](https://webarchive.library.unt.edu/web/20090509210430im_/http://www.cancer.gov/images/spacer.gif) |
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