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ibandronate sodium The sodium salt of ibadronic acid, a synthetic nitrogen-containing bisphosphonate. Ibandronic acid inhibits farnesyl pyrophosphate synthase, resulting in a reduction in geranylgeranyl GTPase signaling proteins and apoptosis of osteoclasts. This agent increases bone mineral density, decreases bone remodeling, inhibits osteoclast-mediated bone resorption, and reduces metastases-related and corticosteroid-related bone pain. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
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Synonym: | ![](https://webarchive.library.unt.edu/web/20090509165258im_/http://www.cancer.gov/images/spacer.gif) | ibandronic acid | | ![](https://webarchive.library.unt.edu/web/20090509165258im_/http://www.cancer.gov/images/spacer.gif) | US brand name: | ![](https://webarchive.library.unt.edu/web/20090509165258im_/http://www.cancer.gov/images/spacer.gif) | Boniva | | ![](https://webarchive.library.unt.edu/web/20090509165258im_/http://www.cancer.gov/images/spacer.gif) | Foreign brand name: | ![](https://webarchive.library.unt.edu/web/20090509165258im_/http://www.cancer.gov/images/spacer.gif) | Bondronate | | ![](https://webarchive.library.unt.edu/web/20090509165258im_/http://www.cancer.gov/images/spacer.gif) |
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