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Safety and Health Topics: |
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| Propylene |
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General Description
Synonyms: Propene; 1-Propene; Methyl Ethene; Methylethylene
OSHA IMIS Code Number: P249
Chemical Abstracts Service (CAS) Registry Number: 115-07-1
NIOSH, Registry of Toxic Effects (RTECS) Identification Number: UC6740000
Department of Transportation Regulation Number (49 CFR 172.101) and Guide: 1075 115
Chemical Description and Physical Properties: Colorless Gas
molecular formula: C3H6
molecular weight: 42.09
boiling point: -47.7°C
vapor pressure: 760 mm Hg @ -47.7°C
melting point: -185.2°C
Potentially hazardous incompatibilities: Incompatible with oxygen. Reacts with oxides of nitrogen to form an explosive product. Reacts violently with oxidizers. Explodes on contact with trifluoromethyl hypofluorite. Explosive polymerization is initiated by lithium nitrate + sulfur dioxide. May also form an ozonide which is explosive at ambient temperatures.
Exposure Limits
American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value (TLV): Simple Asphyxiant; Appendix A4 (Not Classifiable as a Human Carcinogen)
Health Factors
Potential symptoms: Drowsiness; unconsciousness; asphyxia; frostbite (contact with liquid).
Health Effects: Explosive (HE18) CNS effects (HE7); Asphyxiant (HE17).
Affected organ: CNS
Note: Excreted mainly by exhalation. A small amount is metabolized (possibly by CYP2E1) to propylene oxide, a known carcinogen in animals. However, propylene is not carcinogenic in rats and mice.
Date Last Revised: 07/14/2003
Literature Basis:
- International Chemical Safety Cards (WHO/IPCS/ILO): Propylene.
- Filser, J.G., Schmidbauer, R., Rampf, F., Baur, C.M., Pütz, C. and Csanády, G.A.: Toxicokinetics of inhaled propylene in mouse, rat, and human. Toxicol. Appl. Pharmacol. 169: 40-51, 2000.
* All Trademarks are the property of their respective owners.
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| Revised: 29 September 2003 |
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