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ipomeanol
A natural toxic furan isolated from a fungus-infected sweet potato (Ipomoea batatas) with potential antineoplastic activity. Ipomeanol is activated by mixed function oxidases in vivo to its epoxide form, an alkylating agent that covalently binds cell macromolecules. This agent causes cell death by a p53-independent mechanism. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
| Synonym: | | 4-ipomeanol | | | | Chemical structure name: | | 1-(3-furanyl)-4-hydroxy-1-pentanone | | |
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