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clodronate disodium
The disodium salt of a nitrogen-free bisphosphonate analog of naturally occurring pyrophosphate. Clodronate binds to calcium and inhibits osteoclastic bone resorption and hydroxyapatite crystal formation and dissolution, resulting in a reduction of bone turnover. This agent may control malignancy-associated hypercalcemia, inhibit osteolytic bone metastasis and decrease pain. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
| Synonyms: | | clodronic acid, disodium salt
disodium dichloromethylene diphosphonate | | | | Foreign brand names: | | Bonefos
Clasteon
Difosfonal
Loron
Mebonat
Ossiten | | | | Code name: | | CL2MDP | | |
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