|
Office of Population Genomics
Recent Publications
- Collaborative genome-wide association studies of diverse diseases: Programs of the NHGRI's Office of Population Genomics [ncbi.nlm.nih.gov]
Manolio TA. Pharmacogenomics, 10:235-241. 2009.
- Size matters: realistic power calculations for genetic association studies in the genomics age [ncbi.nlm.nih.gov]
Burton PR, Hansell AL, Fortier I, Manolio TA, Khoury MJ, Little J, Elliott P. International Journal of Epidemiology, 38:263-73. 2009.
- Cohort studies and the genetics of complex disease [ncbi.nlm.nih.gov]
Manolio TA. Nature Genetics, 41:5-6. 2009.
- A HapMap harvest of insights into the genetics of common disease [ncbi.nlm.nih.gov]
Manolio TA, Brooks LD, Collins FS. Journal of Clinical Investigation, 118:1590-1625. 2008.
- How to Interpret a Genome-wide Association Study [jama.ama-assn.org]
This article describes the design, interpretation, application, and limitations of GWA studies for clinicians and scientists for whom this evolving science may have great relevance.
- HapMap harvest of insights into the genetics of common disease [ncbi.nlm.nih.gov]
This article discusses the benefits and successes of the International HapMap Project.
- Biorepositories at the bleeding edge [ncbi.nlm.nih.gov]
An article on biorepositories, or "biobanks," discussing their benefits and limitations.
- New models of collaboration in genome-wide association studies: the Genetic Association Information Network
A description of the Genetic Association Information Network (GAIN) and its contribution as a new method of research aiming towards rapid advances in the understanding of the genetics of complex diseases.
- Replicating genotype-phenotype associations
The importance of replication, and how to define it.
- Genes, environment, health, and disease: facing up to complexity [ncbi.nlm.nih.gov]
Understanding the complexity of human disease, and how to identify and interpret gene x gene and gene x environment interactions.
- Merging and emerging cohorts: necessary but not sufficient
A commentary on the benefits and pitfalls of extending existing cohorts versus starting new cohorts.
- Taking our obligations to research participants seriously: disclosing individual results of genetic research [ncbi.nlm.nih.gov]
A commentary on disclosure of results to research participants.
- Genes, environment and the value of prospective cohort studies
This article discusses the importance of prospective cohort studies.
To view the PDFs on this page, you will need Adobe Reader.
Top of page
Last Updated: March 30, 2009
|
|