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Daniel Hwang

Molecular Biologist

Publications

Plasma Acylcarnitine Profiles Suggest Incomplete Fatty Acid ß-Oxidation and Altered Tricarboxylic Cycle Activity in Type 2 Diabetic African-American Women - (Peer Reviewed Journal) - (19-Feb-09)

Inhibition of Nod2 signaling and target gene expression by curcumin - (Peer Reviewed Journal)

Huang, S., Zhao, L., Kim, K., Lee, D., Hwang, D.H. 2008. Inhibition of Nod2 signaling and target gene expression by curcumin. Molecular Pharmacology Vol.74,No.1, 274-284.

The Phosphatidylinositol 3-Kinase/Akt Pathway Negatively Regulates Nod2-Mediated NF-kB Pathway - (Peer Reviewed Journal)

Zhao, L., Lee, J.Y., Hwang, D.H. The Phosphatidylinositol 3-Kinase/Akt Pathway Negatively Regulates Nod2-Mediated NF-kB Pathway. 2008. Biochemical Pharmacology. Vol.75, No.7, pp.1515-1525.

Garlic (Allium sativum) Eextracts Inhibits Lipopolysaccharide-Induced Toll-Like Receptor 4 Dimerization - (Peer Reviewed Journal)

Youn, H., Lim, H., Lee, H., Hwang, D.H., Yang, M., Jeon, R., Ryu, J. 2008. Garlic (Allium sativum) Eextracts Inhibits Lipopolysaccharide-Induced Toll-Like Receptor 4 Dimerization. Bioscience Biotechnology and Biochemistry. 72(2), 368-375.

Acrolein with an alpha, beta-unsaturated Carbonyl Group Inhibits LPS-induced Homodimerization of Toll-like Receptor 4 - (Peer Reviewed Journal)

Lee, J., Lee, J., Lee, M., Hwang, D.H., Youn, H. 2007. Acrolein with an alpha, beta-unsaturated Carbonyl Group Inhibits LPS-induced Homodimerization of Toll-like Receptor 4. Molecules and Cells. Vol.25, No2, 253-257.

Cinnamaldehyde suppresses Toll-like receptor 4 activation mediated through the inhibition of receptor oligomerization - (Peer Reviewed Journal)

Youn, H.S., Lee, J.K., Choi, Y.J., Saitoh, S.I., Miyake, K., Hwang, D.H., Lee, J.Y. 2008. Cinnamaldehyde suppresses Toll-like receptor 4 activation mediated through the inhibition of receptor oligomerization. 2007. Biochemical Pharmacology. Vol.75(2), p.494-502.

The Modulation of Inflammatory Gene Expression by Lipids: Mediation Through Toll-Like Receptors - (Review Article)

Lee, J., Hwang, D.H. The modulation of inflammatory gene expression by lipids: mediation through toll-like receptors. Review Article. 2006. Molecules and Cells, Vol.21,No.2,pp.174-185.

Differential Modulation of Nods Signaling Pathways by Fatty Acids in Human Colonic Epithelial HCT116 cells - (Peer Reviewed Journal)

Zhao, L., Kwon, M., Lee, J.Y., Fukase, K., Inohara, N., Hwang, D.H. Differential Modulation of Nods Signaling Pathways by Fatty Acids in Human Colonic Epithelial HCT116 cells. 2007. Journal of Biological Chemistry. Vol.282, No.16,pp.11618-11628.

Auranofin, As An Anti-Rheumatic Gold Compound Suppresses Lps-Induced Homodimerization of Tlr4 - (Peer Reviewed Journal)

Youn, H.S., Lee, J.Y., Saitoh, S.I., Miyake, K., Hwang, D.H. Auranofin, as an anti-rheumatic gold compound suppresses lps-induced homodimerization of tlr4. Biochemistry and Biophysics Research Communication. 2006.350:866-871

Suppression of Myd88 and Trif-Dependent Signaling Pathways of toll-Like Receptor by (-)-Epigallocatechin-3-Gallate, a Polyphenol Component of Green Tea - (Peer Reviewed Journal)

Youn, H.S., Lee, J.Y., Saotoh, S.I., Miyake, K., Kang, K.W., Choi, Y., Hwang, D.H. 2006. Suppression of myd88- and trif-dependent signaling pathways of toll-like receptor by (-)-epigallocatechin-3-gallate, a polyphenol component of green tea. Biochemical Pharmacology; Elsevier 2006. 72:850:859.

Inhibition of Homodimerization of Toll-Like Receptor 4 by Curcumin - (Peer Reviewed Journal)

Youn, H.S., Saitoh, S.I., Miyake, K., Hwang, D.H. Inhibition of homodimerization of toll-like receptor 4 by curcumin. Biochemical Pharmacology. 2006 Jun 28;72(1):62-69.

Genome-Wide Identification of Peroxisome Proliferator Response Elements Using Integrated Computational Genomics - (Peer Reviewed Journal)

Lemay, D.G., Hwang, D.H. Genome-wide identification of peroxisome proliferator response elements using integrated computational genomics. Journal of Lipid Research. 2006. 47:1583-1587.

Overexpression of the Prostaglandin E2 Receptor Ep2 Results in Enhanced Skin Tumor Development - (Peer Reviewed Journal)

Sung, Y., He, G., Hwang, D.H., Fishcher, S.M. Overexpression of the prostaglandin e2 receptor ep2 results in enhanced skin tumor development. Oncogene. 2006 doi:10.1038/sj.onc.1209538

Specific Inhibition of Myd88-Independent Signaling Pathways of Toll-Like Receptor 3 and 4 by Resveratrol: Molecular Targets Are Tbk1 in Trif Complex* - (Peer Reviewed Journal)

Youn, H.S., Lee, J.Y., Fitzgerald, K.A., Young, H., Akira, S., Hwang, D.H. Specific inhibition of myd88-independent signaling pathways of toll-like receptor 3 and 4 by resveratrol: molecular targets are tbk1 in trif complex*. Journal of Immunology. Sept.2005;175:3339-3346.

The Regulation of the Expression of Inducible Nitric Oxide Synthase by Src-Family Tyrosine Kinase Mediated Through Myd88-Independent Signaling Payways of Toll-Like Receptor 4 - (Peer Reviewed Journal)

Lee, J.Y., Lowell, C.A., Lemay, D.G., Youn, H.S., Rhee, S.H., Sohn, K.H., Jang, B., Ye, J., Chung, J.H., Hwang, D.H. The regulation of the expression of inducible nitric oxide synthase by src-family tyrosine kinase mediated through myd88-independent signaling payways of toll-like receptor 4. Biochemical Pharmacology. 2005, 70:1231-1240.

Src-Family Tyrosine Kinase Inhibitor (Pp1) Suppresses Lps-Induced Expression of Inducible Nitric Oxide Synthase Mediated Through the Inhibition of Interferon B Expression in Macrophages - (Abstract)

Lee, J., Youn, H.S., Lemay, D., Lowell, C.A., Hwang, D.H. Src-family tyrosine kinase inhibitor (pp1) suppresses lps-induced expression of inducible nitric oxide synthase mediated through the inhibition of interferon b expression in macrophages. Experimental Biology. Abstract 829.7 (pge A1453)

Saturated and Polyunsaturated Fatty Acids Reciprocally Modulate Dendritic Cell Functions Mediated Through Tlr4 - (Peer Reviewed Journal)

Weatherill, A., Lee, J., Zhao, L., Lemay, D., Youn, H.S., Hwang, D.H. Saturated and polyunsaturated fatty acids reciprocally modulate dendritic cell functions mediated through tlr4. Journal of Immunology. 2005, 174:5390-5397.

Inhibition of Insulin Sensitivity by Free Fatty Acids Requires Activation of Multiple Serine Kinases in 3t3-L1 Adipocytes - (Peer Reviewed Journal)

Gao, Z., Zhang, X., Zuberi, A., Hwang, D.H., Quon, M.J., Lefevre, M., Ye, J. Inhibition of insulin sensitivity by free fatty acids requires activation of multiple serine kinases in 3t3-l1 adipocytes. Molecular Endocrinology.

Saturated Fatty Acid Activates But Polyunsaturated Fatty Acid Inhibits Toll-Like Receptor 2 Dimerized with Toll-Like Receptor 6 Or 1 - (Peer Reviewed Journal)

Lee, J.Y., Zhao, L., Young, H., Weatherill, A., Tapping, R., Feng, L., Lee, W.H., Fitzgerald, K., Hwang, D.H. Saturated fatty acid activates but polyunsaturated fatty acid inhibits toll-like receptor 2 dimerized with toll-like receptor 6 or 1. Journal of Biological Chemistry.

Reciprocal Modulation of Toll-Like Receptor-4 Signaling Pathways Involving Myd88 and Phosphatidylinositol 3-Kinase/akt by Saturated and Polyunsaturated Fatty Acids - (Peer Reviewed Journal)

Journal Biological Chemustry, Vol.278, No.39, Issue of September 26, pp. 37041-37051, 2003

Last Modified: 05/12/2009

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