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Chemical Sampling Information
Strychnine
 Field Definitions
 Analytical Methods
 Health Guidelines
General Description

NAME: Strychnine

IMIS: 2275

CAS: 57-24-9

NIOSH: RTECS WL2275000; 79005

DOT: UN1692 Poison

DESCRIPTION:

Colorless, odorless solid.
MW: 334
BP: Decomposes
VP: approx. 0 mm
MP:547 F

INCOM: Strong oxidizers

Exposure Limits

OSHA GENERAL INDUSTRY PEL: 0.15 mg/m3

OSHA CONSTRUCTION INDUSTRY PEL: 0.15 mg/m3 TWA

ACGIH TLV: 0.15 mg/m3 TWA

NIOSH REL: 0.15 mg/m3 TWA

Health Factors

SYMPTOM(s): Stiff neck, facial muscles; restlessness, apprehension, increased acuity of perception; increased reflex excitability; cyanosis; tetanic convulsions with opisthotonos

HEALTH EFFECTS: Acute systemic toxicity, CNS (Convulsion and Paralysis) (HE4)

ORGAN: CNS

Monitoring

PRIMARY SAMPLING/ANALYTICAL METHOD (SLC1):



MEDIA: Glass Fiber Filter (37 mm)
MAX V: 1000 Liters   MAX F: 3.0 L/min
ANL 1: High Performance Liquid Chromatography; HPLC/UV
REF: 1 (NIOSH 5016)
CLASS: Fully Validated

COND: Column: C18; Mobile Phase: 50:50 Acetonitrile: Water; Detector Wavelength: 254 nm


Revision Date: 08/24/1992
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