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Abbreviations on this page:
GISP = Gonococcal Isolate Surveillance Project MIC = Minimum inhibitory concentrations N. gonorrhoeae = Neisseria gonorrhoeae NCCLS = National Committee for Clinical Laboratory Standards Some files on this page require Adobe Acrobat or Adobe Reader.
The Gonococcal Isolate Surveillance Project (GISP) was established in 1986 to monitor trends in antimicrobial susceptibilities of strains of N. gonorrhoeae in the United States in order to establish a rational basis for the selection of gonococcal therapies. GISP is a collaborative project between selected sexually transmitted diseases (STD) clinics, five regional laboratories, and the Centers for Disease Control and Prevention (CDC). In GISP, N. gonorrhoeae isolates are collected from the first 25 men with urethral gonorrhea attending STD clinics each month in approximately 28 cities in the United States. At regional laboratories, the susceptibilities of these isolates to penicillin, tetracycline, spectinomycin, ciprofloxacin, ceftriaxone, cefixime, and azithromycin are determined by agar dilution. Minimum inhibitory concentrations (MICs) are measured, and values are interpreted according to criteria recommended by the National Committee for Clinical Laboratory Standards (NCCLS). Sentinel Sites and Regional Laboratories * indicates Regional Laboratories Albuquerque, NM
Page last modified: March 25, 2009 Page last reviewed: March 25, 2009 Content Source: Division of STD Prevention, National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention |
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