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Mouse Models Federated Database
Mouse Model Name
Search All
RPA (variant in DNA binding domain)
Plap-Fs
pUR 288-lacZ 30
Plap-ti
MIh1 (S44F) ATPase
Aprt null
Cyclin Db1 (A870G/exon 5)
P53(S389A)
Xpd SNP
creK5
pUR 288-lacZ 60
p53BAC R72
CycD1bK5(A870G/exon5)
Gal4 E2F1
MCAT Tg
XRCC1 (R194W) ki
Msh6(T1217D)
Fen1 null
Brca1 cre Null
P53(R270H)
P53.R270H/Wap-Cre
P53.R270H/balancer-Cre
P53.R270H/K14Cre
Xpa cond
P53 (P72)
P53 (R72 / R270H)
P53 (P72 / R270H)
p53 BAC P72
ATF3.BK5
Ercc1 cond
Plk1 null
Tdp-1 ko
POLdelta1 (D400A)
Tdg ko
XRCC1 cko
Parp1 null
DNAjC3(tm-gfp)
TCR alpha/beta Tg
P27 (R15W)
ATF3 (T38M)
MIh1 null
Msh2 null
Msh2 (G674A) ATPase
Msh2 (G674D) ATPase
Exo 1 null
PCNA Pol130-104
MBD4 null
XPV null
Chk1 (L449R) non catalytic
Chk1 (R155Q) catalytic
Rb (R654W)
Cyclin D1b tg
Chk2 (I157D)
P53 (R72)
BRCA2 K322N
ATM null
XRCC1 (R280H) ki
Aptx cko (conditional knock out)
Xrcc1 (V86R) ki
XRCC1 (L360R) Ki
Ku70 null
PRKR
WRN (R834C) Ki
WRN (E84A) ki
Plk3 Null
WRN k577m ki
Chk2 1100delC
P27 V109G
WRN K577M Tg
BRCA2 K322Q
Polymerase ε r1382c ki
Polymerase γ r1146c ki
RecQL4
POLdelta1 (L604G) catalytic
POLdelta1 (L604K) catalytic
Gene Name
Search All
None Selected
adenomatosis polyposis coli
APEX nuclease (multifunctional DNA repair enzyme) 1
ataxia telangiectasia mutated (includes complementation groups A, C and D)
breast cancer 1, early onset
cyclin D1 (PRAD1: parathyroid adenomatosis 1)
cyclin H
cyclin-dependent kinase inhibitor 1A (p21, Cip1)
cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CHK1 checkpoint homolog (S. pombe)
CHK2 checkpoint homolog (S. pombe)
cytokine-inducible kinase
E2F transcription factor 1
excision repair cross-complementing rodent repair deficiency, complementation group 1 (includes overlapping antisense sequence)
excision repair cross-complementing rodent repair deficiency, complementation group 2 (xeroderma pigmentosum D)
flap structure-specific endonuclease 1
ligase IV, DNA, ATP-dependent
O-6-methylguanine-DNA methyltransferase
mutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli)
mutS homolog 2, colon cancer, nonpolyposis type 1 (E. coli)
mutS homolog 3 (E. coli)
mutS homolog 4 (E. coli)
mutS homolog 5 (E. coli)
mutS homolog 6 (E. coli)
8-oxoguanine DNA glycosylase
proliferating cell nuclear antigen
polo-like kinase 1 (Drosophila)
PMS2 postmeiotic segregation increased 2 (S. cerevisiae)
polymerase (DNA directed), beta
polymerase (DNA directed), delta 1, catalytic subunit
polymerase (DNA directed), epsilon
polymerase (DNA directed), gamma
polymerase (DNA directed), eta
polymerase (DNA directed) kappa
polymerase (DNA directed), mu
protein kinase, interferon-inducible double stranded RNA dependent
retinoblastoma 1 (including osteosarcoma)
tumor protein p53 (Li-Fraumeni syndrome)
POLs...
Werner syndrome
X-ray repair complementing defective repair in Chinese hamster cells 1
xeroderma pigmentosum, complementation group A
exonuclease 1
adenine phosphoribosyl transferase
activating transcription factor 3
methyl-CpG binding domain protein 4
DnaJ (Hsp40) homolog, subfamily C, member 3
proviral integration site 1
replication protein A1
polo-like kinase 3 (Drosophila)
Thyroid autoantigen 70kDa, Ku antigen
Mitochondrial - Targeted Catalase
amyloid beta (A4) precursor protein (protease nexin-II, Alzheimer disease)
Gene Symbol
Search All
None Selected
APC
APEX1
ATM
BRCA1
CCND1/Cyclin D1
CCNH/cyclin H
CDKN1A/p21
CDKN1B/p27
CHEK1/CHK1
CHEK2/CHK2
CNK/PLK3
E2F1
ERCC1
ERCC2
FEN1
LIG4
MGMT
MLH1
MSH2
MSH3
MSH4
MSH5
MSH6
OGG1
PCNA
PLK1
PMS2
POLB
POLD1
POLE
POLG
POLH
POLK
POLM
PRKR
RB1
TP53
WRN
XRCC1
XPA
EXO1
APRT
ATF3
MBD4
DNAJC3
PIM1
RPA1
PLK3
G22P1
MCAT
APP
Disease
Search All
CANCER
DIABETES
WERNER'S SYNDROME, CANCER
WERNER SYNDROME; AGING
Genetic Mutation Type
Search All
Null
Insertion
Deletion
Point Mutant
loxP Sites
None selected
SNP
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