Interval Training in Young Healthy Individuals - Full Text View

Sponsored by:	Norwegian University of Science and Technology
Information provided by:	Norwegian University of Science and Technology
ClinicalTrials.gov Identifier:	NCT00733941

Purpose

Individuals who participate in regular physical exercise possess a lower prevalence of cardiovascular risk factors such as hypertension, type 2 diabetes, obesity and hypercholesterolemia, and aerobic exercise is therefore considered an important adjuvant therapy in risk factor modification and to promote health.

The main focus of the present study is therefore to detect how rapid it is possible to increase aerobic capacity with interval running exercise.

The hypothesis is that it is possible to improve maximal oxygen uptake faster when increasing training frequency. The total gain in maximal oxygen uptake will however be the same between the two groups when they have performed the same amount of training

Condition	Intervention
Healthy Exercise/Physiology	Behavioral: Training/detraining/retraining

MedlinePlus related topics: Exercise and Physical Fitness

U.S. FDA Resources

Study Type:	Interventional
Study Design:	Treatment, Randomized, Open Label, Active Control, Parallel Assignment, Efficacy Study
Official Title:	Interval Training: Training, Detraining and Retraining; an Interventional Study

Further study details as provided by Norwegian University of Science and Technology:

Primary Outcome Measures:

Oxygen uptake [ Time Frame: Before and after the training-, detraining- and retraining-phase ] [ Designated as safety issue: No ]

Secondary Outcome Measures:

Cardiac function and skeletal muscle enzyme activity [ Time Frame: After training, detraining and retraining ] [ Designated as safety issue: No ]

Estimated Enrollment:	24
Study Start Date:	September 2008
Estimated Study Completion Date:	December 2009
Estimated Primary Completion Date:	June 2009 (Final data collection date for primary outcome measure)

Arms	Assigned Interventions
1 High frequency: Experimental 24 interval exercise performed 8 times per week	Behavioral: Training/detraining/retraining Training phas 8 weeks Detraining phase 8 weeks Retraining phase (8)? weeks
2, Normal frequency: Experimental 24 interval exercises performed 3 times per week	Behavioral: Training/detraining/retraining Training phas 8 weeks Detraining phase 8 weeks Retraining phase (8)? weeks

Detailed Description:

We will perform aerobic interval training at an intensity of 90-95% of maximum heart rate in healthy individuals. The subjects will be randomly assigned to carry out a total of 24 exercise-sessions, either at 3 times per week or 8 times per week.

The two groups will carry out 24 training sessions before 8 weeks of detraining will provide how rapidly aerobic capacity is lost due to inactivity.

After the detraining period a retraining phase is introduced to detect if improvements in aerobic capacity occur more rapidly compared to before the first training period

The subjects will be tested for oxygen uptake, pumping capacity of the heart, blood volume, skeletal muscle enzyme activity, endothelial function.

Eligibility

Ages Eligible for Study:	18 Years to 27 Years
Genders Eligible for Study:	Both
Accepts Healthy Volunteers:	Yes

Criteria

Inclusion Criteria:

BMI<27, non-smokers, train less that 1-2 times per week, VO2max <60 for male and <50 for female.

Exclusion Criteria:

Hypertension, diabetes and cardiovascular disease.

Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT00733941

Contacts

Contact: Øivind Rognmo, PhD	+4773598622	oivind.rognmo@ntnu.no
Contact: Ulrik Wisløff, Professor	+4773598621	ulrik.wisloff@ntnu.no

Locations

Norway
Norwegian University of Science and Technology	Recruiting
Trondheim, Norway, 7020
Sub-Investigator: Tomas Stolen, Msc
NTNU	Recruiting
Trondheim, Norway, 7489
Contact: Ulrik Wisloff, Professor +47 73598638 ulrik.wisloff@ntnu.no
Principal Investigator: Øivind Rognmo, PhD

Sponsors and Collaborators

Norwegian University of Science and Technology

Investigators

Principal Investigator:	Øivind Rognmo, PhD	Norwegian University of Science and Technology
Principal Investigator:	Ulrik Wisløff, Professor	NTNU

More Information

No publications provided

Responsible Party:	Norwegian University of Science and Technology ( Norwegian University of Science and Technology )
Study ID Numbers:	4.2008.1755
Study First Received:	August 12, 2008
Last Updated:	November 3, 2008
ClinicalTrials.gov Identifier:	NCT00733941 History of Changes
Health Authority:	Norway: Norwegian Social Science Data Services; Norway: The National Committees for Research Ethics in Norway

Keywords provided by Norwegian University of Science and Technology:

Interval
Running
Intensity
Arterial diameter

Humanism
Monitoring, Physiologic
Normal
Oxygen Consumption/physiology

Study placed in the following topic categories:

Healthy

ClinicalTrials.gov processed this record on May 07, 2009