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Aerobic Capacity and Body Composition in Colon Cancer Patients
This study is ongoing, but not recruiting participants.
First Received: May 7, 2007   Last Updated: December 19, 2008   History of Changes
Sponsored by: Alberta Cancer Board
Information provided by: Alberta Cancer Board
ClinicalTrials.gov Identifier: NCT00470782
  Purpose

Recent studies have shown that survival after a colorectal cancer diagnosis may be affected by a person's activity level and body size. This research says that for colorectal cancer patients, the less active and more obese they are, the more likely they are to have a cancer recurrence or die from their cancer. Chemotherapy has been shown to reduce activity levels, fitness, and body size in some cancer patients. However, it is not known how chemotherapy specific for colon cancer patients affects their activity levels, fitness, and body size. The main goal of our study will be to look at how chemotherapy treatments affect the fitness, activity levels, and body size in colon cancer patients. In order to do this, we will measure these variables before chemotherapy treatments, and at 1 and 6 months following the end of treatment. Our results will show how chemotherapy affects fitness, activity levels, and body size in colon cancer patients and provide data to help in designing an exercise intervention specifically for colon cancer survivors.


Condition
Colonic Neoplasms

MedlinePlus related topics: Cancer Exercise and Physical Fitness
U.S. FDA Resources
Study Type: Observational
Official Title: Changes in Aerobic Capacity and Body Composition in Colon Cancer Patients Receiving Chemotherapy

Further study details as provided by Alberta Cancer Board:

Estimated Enrollment: 40
Study Start Date: October 2007
  Show Detailed Description

  Eligibility

Ages Eligible for Study:   18 Years and older
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Criteria

Inclusion Criteria:

  • histologically confirmed colon cancer (Stage III and those Stage II patients deemed high-risk
  • approval of the treating oncologist
  • scheduled to received chemotherapy
  • able to understand and provide written informed consent in English
  • 18+ years of age
  • no uncontrolled co-morbidities (including hypertension, cardiac illness, psychiatric condition, etc.)
  • negative ECG as assessed during maximal graded exercise test

Exclusion Criteria:

  • metastatic or recurrent colon cancer patients
  • pregnancy
  • any uncontrolled medical condition that would be a contraindication to exercise (assessed by treating oncologist)
  • unwilling to attend, travel to or participate in the assessments at all 3 time points

In addition, 10 patients meeting all of the eligibility criteria who are not scheduled to receive chemotherapy will also be recruited to the study to serve as "surgery only" controls.

  Contacts and Locations
Please refer to this study by its ClinicalTrials.gov identifier: NCT00470782

Locations
Canada, Alberta
Cross Cancer Institute
Edmonton, Alberta, Canada, T6G 1Z2
Sponsors and Collaborators
Alberta Cancer Board
Investigators
Principal Investigator: Kerry Courneya, PhD University of Alberta
  More Information

No publications provided

Study ID Numbers: GI-5-0064
Study First Received: May 7, 2007
Last Updated: December 19, 2008
ClinicalTrials.gov Identifier: NCT00470782     History of Changes
Health Authority: United States: Institutional Review Board

Keywords provided by Alberta Cancer Board:
colonic neoplasms
exercise
body composition
anthropometry

Study placed in the following topic categories:
Digestive System Diseases
Digestive System Neoplasms
Gastrointestinal Diseases
Colonic Diseases
Gastrointestinal Neoplasms
Intestinal Diseases
Colonic Neoplasms
Intestinal Neoplasms
Colorectal Neoplasms

Additional relevant MeSH terms:
Neoplasms
Digestive System Diseases
Neoplasms by Site
Digestive System Neoplasms
Gastrointestinal Diseases
Colonic Diseases
Gastrointestinal Neoplasms
Intestinal Diseases
Colonic Neoplasms
Intestinal Neoplasms
Colorectal Neoplasms

ClinicalTrials.gov processed this record on May 07, 2009