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Sponsored by: |
Kantonsspital Luzern |
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Information provided by: | Kantonsspital Luzern |
ClinicalTrials.gov Identifier: | NCT00767013 |
We sought to determine whether the dual-source computed tomography assessment of aortic valve stenosis and coronary artery disease is equivalent to or even better than conventional invasive coronary angiography and transthoracic echocardiography.
Condition | Intervention |
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Aortic Valve Stenosis Coronary Disease |
Other: DSCT, TTE |
Study Type: | Interventional |
Study Design: | Diagnostic, Open Label, Single Group Assignment |
Official Title: | Preoperative Assessment of Aortic Valve Stenosis and Coronary Artery Disease: Dual-Source Computed Tomography Compared With Invasive Coronary Angiography and Transthoracic Echocardiography |
Estimated Enrollment: | 65 |
Study Start Date: | May 2007 |
Arms | Assigned Interventions |
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AVS, CAD: Experimental
DSCT
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Other: DSCT, TTE
One assessment each
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Until now invasive coronary angiography has established itself for the assessment of symptomatic aortic valve stenosis. Literature shows a good correlation between MSCT, MRI, TTE and TEE for evaluating the severity of the aortic valve stenosis.
The dual-source computed tomography (DSCT) is capable of assessing coronary arteries with a high sensitivity and specificity in term of relevant stenosis (>50%), due to its excellent spatial and temporal resolution. This study includes the assessment of patients with symptomatic valve stenosis. The severity of the aortic valve stenosis is being assessed by DSCT and TTE. Significant coronary artery stenosis and its localisation are assessed by DSCT and invasive coronary angiography. We examine the correlation between DSCT on one side and either TTE or invasive coronary angiography on the other.
Ages Eligible for Study: | 40 Years and older |
Genders Eligible for Study: | Both |
Accepts Healthy Volunteers: | No |
Inclusion Criteria:
Exclusion Criteria:
Switzerland, Luzern | |
Luzerner Kantonsspital, Department of Cardiology | Recruiting |
Lucerne, Luzern, Switzerland, 6000 | |
Contact: Paul Erne, MD ++41 41 205 51 06 paul.erne@ksl.ch | |
Contact: Christoph Auf der Maur, MD ++41 41 2005 51 48 | |
Principal Investigator: Paul Erne, MD | |
Sub-Investigator: Christoph Auf der Maur, MD |
Principal Investigator: | Paul Erne, MD | Luzerner Kantonsspital |
Responsible Party: | Luzerner Kantonsspital ( Paul Erne ) |
Study ID Numbers: | Cardiac imaging DSCT |
Study First Received: | October 3, 2008 |
Last Updated: | October 3, 2008 |
ClinicalTrials.gov Identifier: | NCT00767013 History of Changes |
Health Authority: | Switzerland: Ethikkommission |
DSCT, coronary artery disease, aortic valve stenosis |
Arterial Occlusive Diseases Pathological Conditions, Anatomical Coronary Disease Heart Diseases Myocardial Ischemia Vascular Diseases |
Constriction, Pathologic Arteriosclerosis Ischemia Aortic Valve Stenosis Coronary Artery Disease Heart Valve Diseases |
Pathological Conditions, Anatomical Arterial Occlusive Diseases Heart Diseases Myocardial Ischemia Vascular Diseases Constriction, Pathologic Arteriosclerosis |
Heart Valve Diseases Coronary Disease Cardiovascular Diseases Aortic Valve Stenosis Coronary Artery Disease Ventricular Outflow Obstruction |