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NIGMS will launch PSI:Biology to support research partnerships between biologists and high-throughput structure determination centers to solve biological problems with knowledge gained from earlier PSI efforts.
Advances led by PSI-supported scientists have had a major technological impact on structural genomics efforts.
Researchers supported by the PSI and the NIGMS Small Business Innovation Research Program have developed a miniature synchrotron that could transform many fields of biomedical research.
Two papers show that X-ray crystallography and nuclear magnetic resonance (NMR) spectroscopy can serve complementary roles in the determination of protein structures.
NIGMS Director Jeremy M. Berg and PSI Director John Norvell highlight the technical achievements made during the PSI pilot phase and goals for the current PSI production phase.
As NIH plans to extend its high-speed structural biology program for another 5 years, researchers remain divided on how best to allocate its shrinking budget.
The Protein Structure Initiative has already come up with one surprise: Proteins apparently come in a limited variety of shapes.