Summaries & Associations of Study Results
TR-273 Trichloroethylene
Target Organs and Levels of Evidence
NTP Technical Report Number 273
Produced from Chemtrack Database 09/19/01
| CHEMICAL/ CAS NUMBER | PEER REVIEW DATE | PRIMARY USES | ROUTE/EXPOSURE LEVELS | STUDY LABORATORY |
|---|---|---|---|---|
| TRICHLOROETHYLENE 79-01-6 |
08/19/86 | DEGREASER, DRY CLEANING SOLVENT, MANUF. ORG. CHEMICALS & PHARMACEUTICALS, HEAT EXCHANGE LIQUID, DILUENT IN PAINTS & ADHESIVES, CAFFEINE EXTRACTANT, TEXTILE PROCESSING, SOLVENT IN PROD'N OF COLOR ADDITIVES FOR FOOD, COSMETICS, DRUGS (HSDB 1990) | Gavage 0,500,1000 MG/KG/50 PER GROUP | Papanicolaou Research Institute |
| LEVELS OF EVIDENCE OF CARCINOGENICITY--ORGAN/TISSUE (NEOPLASM): | ||||
| MR: INADEQUATE STUDY | ||||
| OTHER :CONSIDERATIONS: | DESPITE THESE LIMITATIONS, TUBULAR CELL NEOPLASMS OF THE KIDNEY WERE OBSERVED IN RATS EXPOSED TO TRICHLOROETHYLENE AND INTERSTITIAL CELL NEOPLASMS OF THE TESTIS WERE OBSERVED IN MARSHALL RATS EXPOSED TO TRICHLOROETHYLENE. | |||
| FR: INADEQUATE STUDY | ||||
| TRICHLOROETHYLENE 79-01-6 |
08/19/86 | DEGREASER, DRY CLEANING SOLVENT, MANUF. ORG. CHEMICALS & PHARMACEUTICALS, HEAT EXCHANGE LIQUID, DILUENT IN PAINTS & ADHESIVES, CAFFEINE EXTRACTANT, TEXTILE PROCESSING, SOLVENT IN PROD'N OF COLOR ADDITIVES FOR FOOD, COSMETICS, DRUGS (HSDB 1990) | Gavage 0,500,1000 MG/KG/50 PER GROUP | Papanicolaou Research Institute |
| LEVELS OF EVIDENCE OF CARCINOGENICITY--ORGAN/TISSUE (NEOPLASM): | ||||
| MR: INADEQUATE STUDY | ||||
| OTHER :CONSIDERATIONS: | DESPITE THESE LIMITATIONS, TUBULAR CELL NEOPLASMS OF THE KIDNEY WERE OBSERVED IN RATS EXPOSED TO TRICHLOROETHYLENE AND INTERSTITIAL CELL NEOPLASMS OF THE TESTIS WERE OBSERVED IN MARSHALL RATS EXPOSED TO TRICHLOROETHYLENE. | |||
| FR: INADEQUATE STUDY | ||||
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